Insulin Regulates Hypoxia-Inducible Factor-1α Transcription by Reactive Oxygen Species Sensitive Activation of Sp1 in 3T3-L1 Preadipocyte

Agriculture & Biology

• hypoxia-inducible factor 1 100%
• insulin 55%
• reactive oxygen species 52%
• transcription (genetics) 46%
• transcription factor NF-kappa B 37%
• procollagen-proline dioxygenase 18%
• phosphatidylinositol 3-kinase 16%
• normoxia 15%
• protein kinase C 13%
• assays 13%
• hypoxia 11%
• chromatin 11%
• transcription factors 9%
• promoter regions 9%
• oxygen 8%
• mutation 8%
• proteins 4%

Medicine & Life Sciences

• Hypoxia-Inducible Factor 1 79%
• 3T3-L1 Cells 76%
• Reactive Oxygen Species 50%
• Insulin 42%
• NF-kappa B 26%
• Prolyl Hydroxylases 17%
• Protein Stability 14%
• Chromatin Immunoprecipitation 14%
• Electrophoretic Mobility Shift Assay 13%
• Phosphatidylinositol 3-Kinase 12%
• Protein Kinase C 11%
• Hypoxia 9%
• Transcription Factors 9%
• Oxygen 8%
• Mutation 7%

Chemical Compounds

• Insulin Derivative 64%
• Reactive Oxygen Metabolite 59%
• Phosphatidylinositol 19%
• Dioxygen 15%
• Mutation 13%
• Protein 13%