Insulysin cleaves the APP cytoplasmic fragment at multiple sites

Keyphrases

• Alternative Pathway 50%
• Alzheimer's Disease 50%
• Amyloid-β Peptide 50%
• Caspase 50%
• Cell Lysate 100%
• Cleavage Site 100%
• Cultured Cells 50%
• Degradation in Vitro 50%
• Degradation Pathway 50%
• Degradative Enzymes 100%
• Edman Degradation 50%
• Glycogen Synthase Kinase 3 (GSK3) 50%
• Induced Apoptosis 50%
• Insulysin 100%
• Integral Membrane Protein 50%
• Intracellular Domain 50%
• Knock-in Mouse Model 50%
• Multiple Sites 100%
• Protein Precursors 50%
• Secretase 100%
• Sequence Specificity 50%
• Signal Functions 50%
• Small Peptides 50%
• Turnover Mechanism 50%

Biochemistry, Genetics and Molecular Biology

• Amyloid Protein 50%
• Caspase 50%
• Cell Lysate 100%
• Degradation in Vitro 50%
• Edman Degradation 50%
• Enzyme 100%
• Insulin-Degrading Enzyme 100%
• Insulysin 100%
• Integral Membrane Protein 50%
• Knockout Mouse 50%
• Precursor 50%
• Protein Precursor 50%
• Secretase 100%
• Transcription 50%

Neuroscience

• Alzheimer's Disease 50%
• Amyloid Protein 50%
• Caspase 50%
• Cleft 100%
• Edman Degradation 50%
• In Vitro 50%
• In Vivo 50%
• Insulysin 100%
• Integral Membrane Protein 50%
• Protein Precursor 50%
• Secretase 100%