Interaction of chikungunya virus with the mosquito vector

Konstantin Tsetsarkin, Lark L. Coffey, Scott C. Weaver

Research output: Chapter in Book/Report/Conference proceedingChapter


Chikungunya virus (CHIKV) is an arthropod-borne virus (arbovirus) transmitted by mosquito vectors. Specific aspects of CHIKV interaction with its vectors play a significant role in virus biology, and therefore have a direct influence on the process of CHIKV emergence and the resultant dynamics of outbreaks. The focus of this review is to summarize current understanding of the intrinsic (determined by virus and mosquito genetics) and extrinsic (environmental) factors as well as the complex interplay between them that governs the process of the CHIKVvector interaction, determines CHIKV transmission dynamics and ultimately the process of disease emergence. Recent advances in CHIKV control through vector manipulation are also discussed.

Original languageEnglish (US)
Title of host publicationChikungunya Virus
Subtitle of host publicationAdvances in Biology, Pathogenesis, and Treatment
PublisherSpringer International Publishing
Number of pages28
ISBN (Electronic)9783319429588
ISBN (Print)9783319429564
StatePublished - Jan 1 2016


  • Aedes aegypti
  • Aedes albopictus
  • E1 and E2 glycoproteins mutations
  • Transmission cycle

ASJC Scopus subject areas

  • General Medicine
  • General Immunology and Microbiology


Dive into the research topics of 'Interaction of chikungunya virus with the mosquito vector'. Together they form a unique fingerprint.

Cite this