Interaction of chikungunya virus with the mosquito vector

Konstantin Tsetsarkin, Lark L. Coffey, Scott Weaver

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Chikungunya virus (CHIKV) is an arthropod-borne virus (arbovirus) transmitted by mosquito vectors. Specific aspects of CHIKV interaction with its vectors play a significant role in virus biology, and therefore have a direct influence on the process of CHIKV emergence and the resultant dynamics of outbreaks. The focus of this review is to summarize current understanding of the intrinsic (determined by virus and mosquito genetics) and extrinsic (environmental) factors as well as the complex interplay between them that governs the process of the CHIKVvector interaction, determines CHIKV transmission dynamics and ultimately the process of disease emergence. Recent advances in CHIKV control through vector manipulation are also discussed.

Original languageEnglish (US)
Title of host publicationChikungunya Virus
Subtitle of host publicationAdvances in Biology, Pathogenesis, and Treatment
PublisherSpringer International Publishing
Pages99-126
Number of pages28
ISBN (Electronic)9783319429588
ISBN (Print)9783319429564
DOIs
StatePublished - Jan 1 2016

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Chikungunya virus
Viruses
Arboviruses
Culicidae
Disease Outbreaks
Mosquito Vectors

Keywords

  • Aedes aegypti
  • Aedes albopictus
  • E1 and E2 glycoproteins mutations
  • Transmission cycle

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Tsetsarkin, K., Coffey, L. L., & Weaver, S. (2016). Interaction of chikungunya virus with the mosquito vector. In Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment (pp. 99-126). Springer International Publishing. https://doi.org/10.1007/978-3-319-42958-8_7

Interaction of chikungunya virus with the mosquito vector. / Tsetsarkin, Konstantin; Coffey, Lark L.; Weaver, Scott.

Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment. Springer International Publishing, 2016. p. 99-126.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tsetsarkin, K, Coffey, LL & Weaver, S 2016, Interaction of chikungunya virus with the mosquito vector. in Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment. Springer International Publishing, pp. 99-126. https://doi.org/10.1007/978-3-319-42958-8_7
Tsetsarkin K, Coffey LL, Weaver S. Interaction of chikungunya virus with the mosquito vector. In Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment. Springer International Publishing. 2016. p. 99-126 https://doi.org/10.1007/978-3-319-42958-8_7
Tsetsarkin, Konstantin ; Coffey, Lark L. ; Weaver, Scott. / Interaction of chikungunya virus with the mosquito vector. Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment. Springer International Publishing, 2016. pp. 99-126
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