Abstract
Composition of the erythrocyte ghost membrane obtained from slate-dust-lysed and hypotonically lysed erythrocytes were compared in vitro. The protein and cholesterol contents were unaltered, whilst phospholipid and glycosamine contents decreased significantly in the slate-dust-lysed preparation of erythrocyte ghost membrane. Na+,K+-ATPase activity remained unchanged, whilst acetylcholinesterase activity was decreased slightly by slate dust treatment. Further, binding of silicic acid, dissolving out of slate dust, was observed with a component of erythrocyte ghost membrane protein having molecular weight around 90000 daltons. The significance of the findings is discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 236-240 |
| Number of pages | 5 |
| Journal | Journal of Applied Toxicology |
| Volume | 4 |
| Issue number | 5 |
| State | Published - 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Health, Toxicology and Mutagenesis
- Toxicology
Cite this
Singh, S. V., Das, B., Khan, M., & Rahman, Q. (1984). Interaction of silicate dust with erythrocyte ghost membrane: In vitro studies. Journal of Applied Toxicology, 4(5), 236-240.