Composition of the erythrocyte ghost membrane obtained from slate-dust-lysed and hypotonically lysed erythrocytes were compared in vitro. The protein and cholesterol contents were unaltered, whilst phospholipid and glycosamine contents decreased significantly in the slate-dust-lysed preparation of erythrocyte ghost membrane. Na+,K+-ATPase activity remained unchanged, whilst acetylcholinesterase activity was decreased slightly by slate dust treatment. Further, binding of silicic acid, dissolving out of slate dust, was observed with a component of erythrocyte ghost membrane protein having molecular weight around 90000 daltons. The significance of the findings is discussed.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of Applied Toxicology|
|State||Published - 1984|
ASJC Scopus subject areas
- Health, Toxicology and Mutagenesis