Abstract
Composition of the erythrocyte ghost membrane obtained from slate-dust-lysed and hypotonically lysed erythrocytes were compared in vitro. The protein and cholesterol contents were unaltered, whilst phospholipid and glycosamine contents decreased significantly in the slate-dust-lysed preparation of erythrocyte ghost membrane. Na+,K+-ATPase activity remained unchanged, whilst acetylcholinesterase activity was decreased slightly by slate dust treatment. Further, binding of silicic acid, dissolving out of slate dust, was observed with a component of erythrocyte ghost membrane protein having molecular weight around 90000 daltons. The significance of the findings is discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 236-240 |
| Number of pages | 5 |
| Journal | Journal of Applied Toxicology |
| Volume | 4 |
| Issue number | 5 |
| State | Published - 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Health, Toxicology and Mutagenesis
- Toxicology
Cite this
Interaction of silicate dust with erythrocyte ghost membrane : In vitro studies. / Singh, S. V.; Das, B.; Khan, M; Rahman, Q.
In: Journal of Applied Toxicology, Vol. 4, No. 5, 1984, p. 236-240.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Interaction of silicate dust with erythrocyte ghost membrane
T2 - In vitro studies
AU - Singh, S. V.
AU - Das, B.
AU - Khan, M
AU - Rahman, Q.
PY - 1984
Y1 - 1984
N2 - Composition of the erythrocyte ghost membrane obtained from slate-dust-lysed and hypotonically lysed erythrocytes were compared in vitro. The protein and cholesterol contents were unaltered, whilst phospholipid and glycosamine contents decreased significantly in the slate-dust-lysed preparation of erythrocyte ghost membrane. Na+,K+-ATPase activity remained unchanged, whilst acetylcholinesterase activity was decreased slightly by slate dust treatment. Further, binding of silicic acid, dissolving out of slate dust, was observed with a component of erythrocyte ghost membrane protein having molecular weight around 90000 daltons. The significance of the findings is discussed.
AB - Composition of the erythrocyte ghost membrane obtained from slate-dust-lysed and hypotonically lysed erythrocytes were compared in vitro. The protein and cholesterol contents were unaltered, whilst phospholipid and glycosamine contents decreased significantly in the slate-dust-lysed preparation of erythrocyte ghost membrane. Na+,K+-ATPase activity remained unchanged, whilst acetylcholinesterase activity was decreased slightly by slate dust treatment. Further, binding of silicic acid, dissolving out of slate dust, was observed with a component of erythrocyte ghost membrane protein having molecular weight around 90000 daltons. The significance of the findings is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0021744535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021744535&partnerID=8YFLogxK
M3 - Article
VL - 4
SP - 236
EP - 240
JO - Journal of applied toxicology : JAT
JF - Journal of applied toxicology : JAT
SN - 0260-437X
IS - 5
ER -