Interferon-β 1a and SARS Coronavirus Replication

Lisa E. Hensley, Elizabeth A. Fritz, Peter B. Jahrling, Christopher L. Karp, John W. Huggins, Thomas W. Geisbert

Research output: Contribution to journalArticle

106 Scopus citations


A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon -β 1a potently inhibits SARS coronavirus replication in vitro.

Original languageEnglish (US)
Pages (from-to)317-319
Number of pages3
JournalEmerging infectious diseases
Issue number2
StatePublished - Feb 2004

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Hensley, L. E., Fritz, E. A., Jahrling, P. B., Karp, C. L., Huggins, J. W., & Geisbert, T. W. (2004). Interferon-β 1a and SARS Coronavirus Replication. Emerging infectious diseases, 10(2), 317-319.