Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV

Steven Paul Woods; Julie D. Rippeth; Alan B. Frol; Joel K. Levy; Elizabeth Ryan; Vicki M. Soukup; Charles H. Hinkin; Deborah Lazzaretto; Mariana Cherner; Thomas D. Marcotte; Benjamin B. Gelman; Susan Morgello; Elyse J. Singer; Igor Grant; Robert K. Heaton

doi:10.1080/13803390490509565

Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV

Steven Paul Woods, Julie D. Rippeth, Alan B. Frol, Joel K. Levy, Elizabeth Ryan, Vicki M. Soukup, Charles H. Hinkin, Deborah Lazzaretto, Mariana Cherner, Thomas D. Marcotte, Benjamin B. Gelman, Susan Morgello, Elyse J. Singer, Igor Grant, Robert K. Heaton

Pathology

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Abstract

We examined the interrater reliability (IRR) of clinical ratings of neuropsychological (NP) impairment and neurocognitive diagnoses in HIV. Thirty participants with advanced HIV-infection who were enrolled in a multicenter HIV brain banking research project underwent comprehensive NP and neuromedical evaluations. Using a standardized system of guidelines, neuropsychologists from six participating sites independently assigned clinical ratings of NP impairment, as well as multilevel diagnoses reflecting the inferred etiology of the impairments and their effects on everyday functioning. Findings indicated excellent IRR in rating the presence and severity of NP impairment, but overall modest IRR for neurocognitive diagnoses. Not surprisingly, most diagnostic disagreements concerned the etiology of impairments in persons with medical and neuropsychiatric risk factors in addition to HIV.

Original language	English (US)
Pages (from-to)	759-778
Number of pages	20
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	26
Issue number	6
DOIs	https://doi.org/10.1080/13803390490509565
State	Published - Sep 2004

ASJC Scopus subject areas

Clinical Psychology
Neurology
Clinical Neurology

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Woods, S. P., Rippeth, J. D., Frol, A. B., Levy, J. K., Ryan, E., Soukup, V. M., Hinkin, C. H., Lazzaretto, D., Cherner, M., Marcotte, T. D., Gelman, B. B., Morgello, S., Singer, E. J., Grant, I., & Heaton, R. K. (2004). Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV. Journal of Clinical and Experimental Neuropsychology, 26(6), 759-778. https://doi.org/10.1080/13803390490509565

Woods, SP, Rippeth, JD, Frol, AB, Levy, JK, Ryan, E, Soukup, VM, Hinkin, CH, Lazzaretto, D, Cherner, M, Marcotte, TD, Gelman, BB, Morgello, S, Singer, EJ, Grant, I & Heaton, RK 2004, 'Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV', Journal of Clinical and Experimental Neuropsychology, vol. 26, no. 6, pp. 759-778. https://doi.org/10.1080/13803390490509565

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title = "Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV",

abstract = "We examined the interrater reliability (IRR) of clinical ratings of neuropsychological (NP) impairment and neurocognitive diagnoses in HIV. Thirty participants with advanced HIV-infection who were enrolled in a multicenter HIV brain banking research project underwent comprehensive NP and neuromedical evaluations. Using a standardized system of guidelines, neuropsychologists from six participating sites independently assigned clinical ratings of NP impairment, as well as multilevel diagnoses reflecting the inferred etiology of the impairments and their effects on everyday functioning. Findings indicated excellent IRR in rating the presence and severity of NP impairment, but overall modest IRR for neurocognitive diagnoses. Not surprisingly, most diagnostic disagreements concerned the etiology of impairments in persons with medical and neuropsychiatric risk factors in addition to HIV.",

author = "Woods, {Steven Paul} and Rippeth, {Julie D.} and Frol, {Alan B.} and Levy, {Joel K.} and Elizabeth Ryan and Soukup, {Vicki M.} and Hinkin, {Charles H.} and Deborah Lazzaretto and Mariana Cherner and Marcotte, {Thomas D.} and Gelman, {Benjamin B.} and Susan Morgello and Singer, {Elyse J.} and Igor Grant and Heaton, {Robert K.}",

note = "Funding Information: This study was supported by grants R24MH59656, R24MH59724, R24MH59745, R24NS38841, and R24NS45491 from the National Institute of Health, as well as by center award P30 MH62512-01 (HNRC) from the National Institutes of Mental Health. We are grateful to R. Michelle Brill, Yanira Lopez LoCoco, and Monica Rivera Mindt, Ph.D. for their contributions to the NNTC Quality Assurance process. We also thank Emily Conover and Kimberly Ann Halfman for their assistance in preparing the manuscript.",

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doi = "10.1080/13803390490509565",

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AU - Woods, Steven Paul

AU - Rippeth, Julie D.

AU - Frol, Alan B.

AU - Levy, Joel K.

AU - Ryan, Elizabeth

AU - Soukup, Vicki M.

AU - Hinkin, Charles H.

AU - Lazzaretto, Deborah

AU - Cherner, Mariana

AU - Marcotte, Thomas D.

AU - Gelman, Benjamin B.

AU - Morgello, Susan

AU - Singer, Elyse J.

AU - Grant, Igor

AU - Heaton, Robert K.

N1 - Funding Information: This study was supported by grants R24MH59656, R24MH59724, R24MH59745, R24NS38841, and R24NS45491 from the National Institute of Health, as well as by center award P30 MH62512-01 (HNRC) from the National Institutes of Mental Health. We are grateful to R. Michelle Brill, Yanira Lopez LoCoco, and Monica Rivera Mindt, Ph.D. for their contributions to the NNTC Quality Assurance process. We also thank Emily Conover and Kimberly Ann Halfman for their assistance in preparing the manuscript.

PY - 2004/9

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AB - We examined the interrater reliability (IRR) of clinical ratings of neuropsychological (NP) impairment and neurocognitive diagnoses in HIV. Thirty participants with advanced HIV-infection who were enrolled in a multicenter HIV brain banking research project underwent comprehensive NP and neuromedical evaluations. Using a standardized system of guidelines, neuropsychologists from six participating sites independently assigned clinical ratings of NP impairment, as well as multilevel diagnoses reflecting the inferred etiology of the impairments and their effects on everyday functioning. Findings indicated excellent IRR in rating the presence and severity of NP impairment, but overall modest IRR for neurocognitive diagnoses. Not surprisingly, most diagnostic disagreements concerned the etiology of impairments in persons with medical and neuropsychiatric risk factors in addition to HIV.

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Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV

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