Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV

Steven Paul Woods, Julie D. Rippeth, Alan B. Frol, Joel K. Levy, Elizabeth Ryan, Vicki M. Soukup, Charles H. Hinkin, Deborah Lazzaretto, Mariana Cherner, Thomas D. Marcotte, Benjamin B. Gelman, Susan Morgello, Elyse J. Singer, Igor Grant, Robert K. Heaton

Research output: Contribution to journalArticlepeer-review

267 Scopus citations


We examined the interrater reliability (IRR) of clinical ratings of neuropsychological (NP) impairment and neurocognitive diagnoses in HIV. Thirty participants with advanced HIV-infection who were enrolled in a multicenter HIV brain banking research project underwent comprehensive NP and neuromedical evaluations. Using a standardized system of guidelines, neuropsychologists from six participating sites independently assigned clinical ratings of NP impairment, as well as multilevel diagnoses reflecting the inferred etiology of the impairments and their effects on everyday functioning. Findings indicated excellent IRR in rating the presence and severity of NP impairment, but overall modest IRR for neurocognitive diagnoses. Not surprisingly, most diagnostic disagreements concerned the etiology of impairments in persons with medical and neuropsychiatric risk factors in addition to HIV.

Original languageEnglish (US)
Pages (from-to)759-778
Number of pages20
JournalJournal of Clinical and Experimental Neuropsychology
Issue number6
StatePublished - Sep 2004

ASJC Scopus subject areas

  • Clinical Psychology
  • Neurology
  • Clinical Neurology


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