Intra-abdominal splenosis mimicking metastatic cancer

Nicholas J. Short, Teresa G. Hayes, Peeyush Bhargava

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. Confirmation of splenic tissue can be made by technetium-99m (Tc-99m) sulfur colloid scintigraphy or with Tc-99m heat-damaged red blood cells; however, in some cases, biopsy may be required for definitive diagnosis. Here, the authors present a patient with a remote history of posttraumatic splenectomy who was discovered to have multiple intra-abdominal nodules by CT scan. A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intra-abdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging.

Original languageEnglish (US)
Pages (from-to)246-249
Number of pages4
JournalAmerican Journal of the Medical Sciences
Volume341
Issue number3
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

Fingerprint

Splenosis
Technetium
Technetium Tc 99m Sulfur Colloid
Emission-Computed Tomography
Neoplasms
Splenectomy
Radionuclide Imaging
Positron-Emission Tomography
Hot Temperature
Erythrocytes
Biopsy
Wounds and Injuries

Keywords

  • Abdominal mass
  • SPECT-CT
  • Splenosis
  • Tc-99m sulfur colloid scintigraphy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Intra-abdominal splenosis mimicking metastatic cancer. / Short, Nicholas J.; Hayes, Teresa G.; Bhargava, Peeyush.

In: American Journal of the Medical Sciences, Vol. 341, No. 3, 01.01.2011, p. 246-249.

Research output: Contribution to journalArticle

Short, Nicholas J. ; Hayes, Teresa G. ; Bhargava, Peeyush. / Intra-abdominal splenosis mimicking metastatic cancer. In: American Journal of the Medical Sciences. 2011 ; Vol. 341, No. 3. pp. 246-249.
@article{32441b847c87406a9ecdeb4d301ba75b,
title = "Intra-abdominal splenosis mimicking metastatic cancer",
abstract = "Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. Confirmation of splenic tissue can be made by technetium-99m (Tc-99m) sulfur colloid scintigraphy or with Tc-99m heat-damaged red blood cells; however, in some cases, biopsy may be required for definitive diagnosis. Here, the authors present a patient with a remote history of posttraumatic splenectomy who was discovered to have multiple intra-abdominal nodules by CT scan. A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intra-abdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging.",
keywords = "Abdominal mass, SPECT-CT, Splenosis, Tc-99m sulfur colloid scintigraphy",
author = "Short, {Nicholas J.} and Hayes, {Teresa G.} and Peeyush Bhargava",
year = "2011",
month = "1",
day = "1",
doi = "10.1097/MAJ.0b013e318202893f",
language = "English (US)",
volume = "341",
pages = "246--249",
journal = "American Journal of the Medical Sciences",
issn = "0002-9629",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Intra-abdominal splenosis mimicking metastatic cancer

AU - Short, Nicholas J.

AU - Hayes, Teresa G.

AU - Bhargava, Peeyush

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. Confirmation of splenic tissue can be made by technetium-99m (Tc-99m) sulfur colloid scintigraphy or with Tc-99m heat-damaged red blood cells; however, in some cases, biopsy may be required for definitive diagnosis. Here, the authors present a patient with a remote history of posttraumatic splenectomy who was discovered to have multiple intra-abdominal nodules by CT scan. A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intra-abdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging.

AB - Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. Confirmation of splenic tissue can be made by technetium-99m (Tc-99m) sulfur colloid scintigraphy or with Tc-99m heat-damaged red blood cells; however, in some cases, biopsy may be required for definitive diagnosis. Here, the authors present a patient with a remote history of posttraumatic splenectomy who was discovered to have multiple intra-abdominal nodules by CT scan. A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intra-abdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging.

KW - Abdominal mass

KW - SPECT-CT

KW - Splenosis

KW - Tc-99m sulfur colloid scintigraphy

UR - http://www.scopus.com/inward/record.url?scp=79952046542&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952046542&partnerID=8YFLogxK

U2 - 10.1097/MAJ.0b013e318202893f

DO - 10.1097/MAJ.0b013e318202893f

M3 - Article

C2 - 21446083

AN - SCOPUS:79952046542

VL - 341

SP - 246

EP - 249

JO - American Journal of the Medical Sciences

JF - American Journal of the Medical Sciences

SN - 0002-9629

IS - 3

ER -