Intravenous Immune Globulin Therapy: Treatment of a Patient With Severe Immunodeficiency, Chronic Malabsorption, and Fulminant Septicemia

Emilio Gonzalez, Brock G. Guernsey, Naomi B. Ingrim, Yukinobu Ichikawa, Jerry C. Daniels

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Biweekly 200 mg/kg infusions of immune globulin (Gamimune) were given to a 46-year-old woman with severe common variable immunodeficiency, bronchiectasis, and chronic diarrhea with malabsorption. Failure to achieve therapeutically effective serum IgG concentrations in the face of fulminant sepsis was accompanied by a shortened serum IgG half-life of 10.6 days. Currently recommended doses of 200 mg/kg may prove inadequate in very ill patients with sepsis and malabsorption.

Original languageEnglish (US)
Pages (from-to)945-946
Number of pages2
JournalArchives of Internal Medicine
Volume145
Issue number5
DOIs
StatePublished - 1985

Fingerprint

Intravenous Immunoglobulins
Sepsis
Immunoglobulin G
Common Variable Immunodeficiency
Bronchiectasis
Serum
Half-Life
Immunoglobulins
Diarrhea
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Intravenous Immune Globulin Therapy : Treatment of a Patient With Severe Immunodeficiency, Chronic Malabsorption, and Fulminant Septicemia. / Gonzalez, Emilio; Guernsey, Brock G.; Ingrim, Naomi B.; Ichikawa, Yukinobu; Daniels, Jerry C.

In: Archives of Internal Medicine, Vol. 145, No. 5, 1985, p. 945-946.

Research output: Contribution to journalArticle

Gonzalez, Emilio ; Guernsey, Brock G. ; Ingrim, Naomi B. ; Ichikawa, Yukinobu ; Daniels, Jerry C. / Intravenous Immune Globulin Therapy : Treatment of a Patient With Severe Immunodeficiency, Chronic Malabsorption, and Fulminant Septicemia. In: Archives of Internal Medicine. 1985 ; Vol. 145, No. 5. pp. 945-946.
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