Intravenous Immune Globulin Therapy: Treatment of a Patient With Severe Immunodeficiency, Chronic Malabsorption, and Fulminant Septicemia

Emilio Gonzalez, Brock G. Guernsey, Naomi B. Ingrim, Yukinobu Ichikawa, Jerry C. Daniels

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Biweekly 200 mg/kg infusions of immune globulin (Gamimune) were given to a 46-year-old woman with severe common variable immunodeficiency, bronchiectasis, and chronic diarrhea with malabsorption. Failure to achieve therapeutically effective serum IgG concentrations in the face of fulminant sepsis was accompanied by a shortened serum IgG half-life of 10.6 days. Currently recommended doses of 200 mg/kg may prove inadequate in very ill patients with sepsis and malabsorption.

Original languageEnglish (US)
Pages (from-to)945-946
Number of pages2
JournalArchives of Internal Medicine
Volume145
Issue number5
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'Intravenous Immune Globulin Therapy: Treatment of a Patient With Severe Immunodeficiency, Chronic Malabsorption, and Fulminant Septicemia'. Together they form a unique fingerprint.

  • Cite this