Invasive papillomatosis and squamous carcinoma complicating juvenile laryngeal papillomatosis

V. J. Schnadig, W. D. Clark, T. J. Clegg, C. S. Yao

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Juvenile laryngeal papillomatosis (JLP), usually a benign, self-limited disease, occasionally has a highly aggressive course characterized by extension of neoplastic cells into the tracheobronchial tree, lung, and soft tissues. Less frequently, squamous carcinoma has arisen in JLP, most commonly following radiation therapy. Rarely, carcinoma has occurred without previous irradition, but distant metastases do not generally occur. We describe a 14-year-old boy, with a particularly aggressive form of JLP, who developed invasion of the lungs, intrapulmonary lymph nodes, and arteries by cytologically benign neoplastic tissue. He also developed a metastasizing squamous carcinoma of the lung and humoral hypercalcemia of malignancy. A discussion of the implications of the case and a review of the current literature are provided.

Original languageEnglish (US)
Pages (from-to)966-971
Number of pages6
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume112
Issue number9
StatePublished - 1986

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Papilloma
Squamous Cell Carcinoma
Lung
Radiotherapy
Arteries
Lymph Nodes
Neoplasm Metastasis
Carcinoma
Laryngeal papillomatosis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Invasive papillomatosis and squamous carcinoma complicating juvenile laryngeal papillomatosis. / Schnadig, V. J.; Clark, W. D.; Clegg, T. J.; Yao, C. S.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 112, No. 9, 1986, p. 966-971.

Research output: Contribution to journalArticle

Schnadig, V. J. ; Clark, W. D. ; Clegg, T. J. ; Yao, C. S. / Invasive papillomatosis and squamous carcinoma complicating juvenile laryngeal papillomatosis. In: Archives of Otolaryngology - Head and Neck Surgery. 1986 ; Vol. 112, No. 9. pp. 966-971.
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