Abstract
GH is a potent anabolic agent that offers distinct advantages to the hypercatabolic paediatric burns patient. GH can be administered with minimal risk of untoward side-effects in this patient group. GH reduces the catabolic effects of trauma, both directly and indirectly, through stimulation of protein synthesis. Accelerated wound healing and reduction in tissue-wasting effects are clear benefits that reduce the overall morbidity associated with burn injury in children. Further applications of GH treatment will stem from ongoing investigations that are examining alternative delivery methods, long- term treatment beyond the acute hospitalization phase, and combination therapy with β-blockers, antiglucocorticoids or other growth factors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 99-105 |
| Number of pages | 7 |
| Journal | Growth Hormone and IGF Research |
| Volume | 8 |
| Issue number | SUPPL. B |
| State | Published - 1998 |
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ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Is there a role for growth hormone in the clinical management of burn injuries? / Ramirez, R. J.; Wolf, Steven; Herndon, David.
In: Growth Hormone and IGF Research, Vol. 8, No. SUPPL. B, 1998, p. 99-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Is there a role for growth hormone in the clinical management of burn injuries?
AU - Ramirez, R. J.
AU - Wolf, Steven
AU - Herndon, David
PY - 1998
Y1 - 1998
N2 - GH is a potent anabolic agent that offers distinct advantages to the hypercatabolic paediatric burns patient. GH can be administered with minimal risk of untoward side-effects in this patient group. GH reduces the catabolic effects of trauma, both directly and indirectly, through stimulation of protein synthesis. Accelerated wound healing and reduction in tissue-wasting effects are clear benefits that reduce the overall morbidity associated with burn injury in children. Further applications of GH treatment will stem from ongoing investigations that are examining alternative delivery methods, long- term treatment beyond the acute hospitalization phase, and combination therapy with β-blockers, antiglucocorticoids or other growth factors.
AB - GH is a potent anabolic agent that offers distinct advantages to the hypercatabolic paediatric burns patient. GH can be administered with minimal risk of untoward side-effects in this patient group. GH reduces the catabolic effects of trauma, both directly and indirectly, through stimulation of protein synthesis. Accelerated wound healing and reduction in tissue-wasting effects are clear benefits that reduce the overall morbidity associated with burn injury in children. Further applications of GH treatment will stem from ongoing investigations that are examining alternative delivery methods, long- term treatment beyond the acute hospitalization phase, and combination therapy with β-blockers, antiglucocorticoids or other growth factors.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032453534&partnerID=8YFLogxK
M3 - Article
VL - 8
SP - 99
EP - 105
JO - Endocrinology and Metabolism
JF - Endocrinology and Metabolism
SN - 1096-6374
IS - SUPPL. B
ER -