Isolation and Characterization of Madariaga Virus from a Horse in Paraíba State, Brazil

M. L.C.R. Silva, A. J. Auguste, A. C.B. Terzian, D. Vedovello, F. Riet-Correa, V. M.K. Macário, M. P.G. Mourão, L. S. Ullmann, J. P. Araújo, S. C. Weaver, M. L. Nogueira

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obtained from a horse in Brazil. Our results support previous phylogenetic studies showing there are three genetically distinct MADV lineages. The MADV isolate from Paraíba State belongs to the South American lineage III and is closely related to Peruvian, Colombian and Venezuelan isolates.

Original languageEnglish (US)
Pages (from-to)990-993
Number of pages4
JournalTransboundary and Emerging Diseases
Issue number3
StatePublished - Jun 2017


  • Alphavirus
  • Madariaga virus
  • arboviruses
  • eastern equine encephalitis virus
  • horse

ASJC Scopus subject areas

  • General Immunology and Microbiology
  • General Veterinary


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