Isoniazid and iproniazid: Activation of metabolites to toxic intermediates in man and rat

Keyphrases

• Toxic Intermediates 100%
• Iproniazid 100%
• Macromolecules 50%
• High Incidence 50%
• Liver 50%
• Cytochrome P450 Enzymes 50%
• Covalent Binding 50%
• Clinical Application 50%
• Liver Injury 50%
• Alkylating Agents 50%
• Anti-tuberculosis Drugs 50%
• Antidepressants 50%
• Rat Liver Microsomes 50%
• Cell Necrosis 50%
• Human Liver Microsomes 50%
• Monosubstituted 50%
• Hydrazine 50%
• Acetylhydrazine 50%
• Acylating Agent 50%
• Reactive Electrophiles 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Isoniazid 100%
• Iproniazid 100%
• Cytochrome P450 50%
• Liver Injury 50%
• Alkylating Agent 50%
• Necrosis 50%
• Tuberculostatic Agent 50%
• Antidepressant 50%
• Electrophile 50%
• Acetohydrazide 50%
• Hydrazine Derivative 50%