Japanese Encephalitis Virus

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Japanese encephalitis virus (JEV) is a member of the genus Flavivirus, family Flaviviridae. It causes a rural, mosquito-borne, zoonotic viral disease that is a major public health problem in many Asian countries. The natural cycle involves rice-field breeding mosquitoes and domestic pigs or wading ardeids (e.g., egrets and herons). The most important vector is Culex tritaeniorhynchus, which is found in most parts of Asia and breeds in water pools and flooded rice fields. Humans and most other vertebrates are 'dead-end' hosts, producing low viremias, such that mosquitoes cannot be infected while feeding on them. Japanese encephalitis (JE) is characterized by infection of the central nervous system. It is the most important arthropod-borne virus encephalitis. At least 50 000 clinical cases of JE are reported each year. The case-fatality rate is approximately 25% and up to 70% of those who survive infection develop neurological sequelae. JE is the most important veterinary flavivirus disease. In addition to wild boars, two animal hosts are considered to be important: horses and pigs. Horses become encephalitic and are considered to be dead-end hosts, whereas JEV induces abortion in pigs, considered to be a major peridomestic amplifying host.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Virology
PublisherElsevier Ltd
Pages182-188
Number of pages7
ISBN (Print)9780123744104
DOIs
StatePublished - Jan 1 2008

Fingerprint

Japanese Encephalitis Virus
Japanese Encephalitis
Culicidae
Flavivirus
Sus scrofa
Horses
Arbovirus Encephalitis
Swine
Flaviviridae
Arboviruses
Central Nervous System Infections
Culex
Viremia
Zoonoses
Virus Diseases
Breeding
Vertebrates
Public Health
Mortality
Water

Keywords

  • Abortion
  • Asia
  • Birds
  • Encephalitis
  • Flaviviridae
  • Flavivirus
  • Horses
  • Mosquito
  • Neurological
  • Pigs
  • Psychiatric sequelae
  • Stillbirth

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

Cite this

Barrett, A. (2008). Japanese Encephalitis Virus. In Encyclopedia of Virology (pp. 182-188). Elsevier Ltd. https://doi.org/10.1016/B978-012374410-4.00434-9

Japanese Encephalitis Virus. / Barrett, Alan.

Encyclopedia of Virology. Elsevier Ltd, 2008. p. 182-188.

Research output: Chapter in Book/Report/Conference proceedingChapter

Barrett, A 2008, Japanese Encephalitis Virus. in Encyclopedia of Virology. Elsevier Ltd, pp. 182-188. https://doi.org/10.1016/B978-012374410-4.00434-9
Barrett A. Japanese Encephalitis Virus. In Encyclopedia of Virology. Elsevier Ltd. 2008. p. 182-188 https://doi.org/10.1016/B978-012374410-4.00434-9
Barrett, Alan. / Japanese Encephalitis Virus. Encyclopedia of Virology. Elsevier Ltd, 2008. pp. 182-188
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