Jejunal adenocarcinoma presenting as a primary ovarian carcinoma

Gokhan Kilic, Maria Abadi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective. The aim of this case report was to evaluate the impact of immunohistochemical markers in diagnosing the primary site of adenocarcinoma in the abdominopelvic region. Methods. Surgicopathologic data were obtained from laparotomy and necropsy. Paraffin-embedded tissue from the ovary and jejunum was stained with hematoxylin and eosin, as well as with immunohistochemical stains for cytokeratin 20 and cytokeratin 7. Results. A 53-year-old African American woman underwent an emergency laparotomy due to small bowel obstruction. During the operation, in addition to a complex adnexal mass as the cause of obstruction, a small solid jejunal tumor was also identified. Pathologic evaluation of the two sites demonstrated an infiltrating moderately to poorly differentiated adenocarcinoma with mucinous features. The malignant cells from both intestinal and ovarian sites showed immunoreactivity for cytokeratin 20 and revealed negative staining for cytokeratin 7. These results confirmed the diagnosis of intestinal primary with ovarian metastasis, which was initially misdiagnosed as an ovarian primary. Conclusion. Given the potential difficulty in determining the primary site of these tumors, immunohistochemistry proved to be a useful tool in reaching the correct diagnosis. (C) 2000 Academic Press.

Original languageEnglish (US)
Pages (from-to)255-258
Number of pages4
JournalGynecologic Oncology
Volume78
Issue number2
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

Keratin-20
Keratin-7
Laparotomy
Adenocarcinoma
Carcinoma
Mucinous Adenocarcinoma
Negative Staining
Jejunum
Hematoxylin
Eosine Yellowish-(YS)
Diagnostic Errors
African Americans
Paraffin
Ovary
Neoplasms
Emergencies
Coloring Agents
Immunohistochemistry
Neoplasm Metastasis

Keywords

  • Adenocarcinoma
  • Ovary
  • Small bowel

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Jejunal adenocarcinoma presenting as a primary ovarian carcinoma. / Kilic, Gokhan; Abadi, Maria.

In: Gynecologic Oncology, Vol. 78, No. 2, 2000, p. 255-258.

Research output: Contribution to journalArticle

@article{437e300d68eb4413be3ae28af4341bd5,
title = "Jejunal adenocarcinoma presenting as a primary ovarian carcinoma",
abstract = "Objective. The aim of this case report was to evaluate the impact of immunohistochemical markers in diagnosing the primary site of adenocarcinoma in the abdominopelvic region. Methods. Surgicopathologic data were obtained from laparotomy and necropsy. Paraffin-embedded tissue from the ovary and jejunum was stained with hematoxylin and eosin, as well as with immunohistochemical stains for cytokeratin 20 and cytokeratin 7. Results. A 53-year-old African American woman underwent an emergency laparotomy due to small bowel obstruction. During the operation, in addition to a complex adnexal mass as the cause of obstruction, a small solid jejunal tumor was also identified. Pathologic evaluation of the two sites demonstrated an infiltrating moderately to poorly differentiated adenocarcinoma with mucinous features. The malignant cells from both intestinal and ovarian sites showed immunoreactivity for cytokeratin 20 and revealed negative staining for cytokeratin 7. These results confirmed the diagnosis of intestinal primary with ovarian metastasis, which was initially misdiagnosed as an ovarian primary. Conclusion. Given the potential difficulty in determining the primary site of these tumors, immunohistochemistry proved to be a useful tool in reaching the correct diagnosis. (C) 2000 Academic Press.",
keywords = "Adenocarcinoma, Ovary, Small bowel",
author = "Gokhan Kilic and Maria Abadi",
year = "2000",
doi = "10.1006/gyno.2000.5872",
language = "English (US)",
volume = "78",
pages = "255--258",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Jejunal adenocarcinoma presenting as a primary ovarian carcinoma

AU - Kilic, Gokhan

AU - Abadi, Maria

PY - 2000

Y1 - 2000

N2 - Objective. The aim of this case report was to evaluate the impact of immunohistochemical markers in diagnosing the primary site of adenocarcinoma in the abdominopelvic region. Methods. Surgicopathologic data were obtained from laparotomy and necropsy. Paraffin-embedded tissue from the ovary and jejunum was stained with hematoxylin and eosin, as well as with immunohistochemical stains for cytokeratin 20 and cytokeratin 7. Results. A 53-year-old African American woman underwent an emergency laparotomy due to small bowel obstruction. During the operation, in addition to a complex adnexal mass as the cause of obstruction, a small solid jejunal tumor was also identified. Pathologic evaluation of the two sites demonstrated an infiltrating moderately to poorly differentiated adenocarcinoma with mucinous features. The malignant cells from both intestinal and ovarian sites showed immunoreactivity for cytokeratin 20 and revealed negative staining for cytokeratin 7. These results confirmed the diagnosis of intestinal primary with ovarian metastasis, which was initially misdiagnosed as an ovarian primary. Conclusion. Given the potential difficulty in determining the primary site of these tumors, immunohistochemistry proved to be a useful tool in reaching the correct diagnosis. (C) 2000 Academic Press.

AB - Objective. The aim of this case report was to evaluate the impact of immunohistochemical markers in diagnosing the primary site of adenocarcinoma in the abdominopelvic region. Methods. Surgicopathologic data were obtained from laparotomy and necropsy. Paraffin-embedded tissue from the ovary and jejunum was stained with hematoxylin and eosin, as well as with immunohistochemical stains for cytokeratin 20 and cytokeratin 7. Results. A 53-year-old African American woman underwent an emergency laparotomy due to small bowel obstruction. During the operation, in addition to a complex adnexal mass as the cause of obstruction, a small solid jejunal tumor was also identified. Pathologic evaluation of the two sites demonstrated an infiltrating moderately to poorly differentiated adenocarcinoma with mucinous features. The malignant cells from both intestinal and ovarian sites showed immunoreactivity for cytokeratin 20 and revealed negative staining for cytokeratin 7. These results confirmed the diagnosis of intestinal primary with ovarian metastasis, which was initially misdiagnosed as an ovarian primary. Conclusion. Given the potential difficulty in determining the primary site of these tumors, immunohistochemistry proved to be a useful tool in reaching the correct diagnosis. (C) 2000 Academic Press.

KW - Adenocarcinoma

KW - Ovary

KW - Small bowel

UR - http://www.scopus.com/inward/record.url?scp=0033842651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033842651&partnerID=8YFLogxK

U2 - 10.1006/gyno.2000.5872

DO - 10.1006/gyno.2000.5872

M3 - Article

VL - 78

SP - 255

EP - 258

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 2

ER -