Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand; James T. Robinson; Muhammad S. Shamim; Ido Machol; Jill P. Mesirov; Eric S. Lander; Erez Lieberman Aiden

doi:10.1016/j.cels.2015.07.012

Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Neva C. Durand
, James T. Robinson
, Muhammad S. Shamim
, Ido Machol
, Jill P. Mesirov
, Eric S. Lander
, Erez Lieberman Aiden

Research output: Contribution to journal › Article › peer-review

1618 Scopus citations

Abstract

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

Original language	English (US)
Pages (from-to)	99-101
Number of pages	3
Journal	Cell Systems
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.cels.2015.07.012
State	Published - Jul 27 2016
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Cell Biology

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10.1016/j.cels.2015.07.012

Cite this

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title = "Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom",

abstract = "Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.",

author = "Durand, \{Neva C.\} and Robinson, \{James T.\} and Shamim, \{Muhammad S.\} and Ido Machol and Mesirov, \{Jill P.\} and Lander, \{Eric S.\} and Aiden, \{Erez Lieberman\}",

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AU - Durand, Neva C.

AU - Robinson, James T.

AU - Shamim, Muhammad S.

AU - Machol, Ido

AU - Mesirov, Jill P.

AU - Lander, Eric S.

AU - Aiden, Erez Lieberman

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AB - Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

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JO - Cell Systems

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IS - 1

ER -

Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Abstract

ASJC Scopus subject areas

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