Jungle yellow fever

clinical and laboratorial studies emphasizing viremia on a human case.

E. S. Nassar, E. L. Chamelet, T. L. Coimbra, L. T. de Souza, A. Suzuki, I. B. Ferreira, M. V. da Silva, I. M. Rocco, A. P. Travassos da Rosa

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The authors report the clinical, laboratorial and epidemiological aspects of a human case of jungle yellow fever. The patient suffered from fever, chills, sweating, headaches, backaches, myalgia, epigastric pains, nausea, vomiting, diarrhea and prostration. He was unvaccinated and had been working in areas where cases of jungle yellow fever had been confirmed. Investigations concerning the yellow fever virus were performed. Blood samples were collected on several days in the course of the illness. Three of these samples (those obtained on days 5, 7 and 10) were inoculated into suckling mice in attempt to isolate virus and to titrate the viremia level. Serological surveys were carried out by using the IgM Antibodies Capture Enzyme Linked Immunosorbent Assay (MAC-ELISA), Complement Fixation (CF), Hemagglutination Inhibition (HI) and Neutralization (N) tests. The yellow fever virus, recovered from the two first samples and the virus titration, showed high level of viremia. After that, specific antibodies appeared in all samples. The interval between the end of the viremia and the appearance of the antibodies was associated with the worsening of clinical symptoms, including bleeding of the mucous membrane. One must be aware of the risk of having a urban epidemics in areas where Aedes aegypti is found in high infestation indexes.

Original languageEnglish (US)
Pages (from-to)337-341
Number of pages5
JournalRevista do Instituto de Medicina Tropical de São Paulo
Volume37
Issue number4
StatePublished - Jul 1995
Externally publishedYes

Fingerprint

Yellow Fever
Viremia
Yellow fever virus
Antibodies
Enzyme-Linked Immunosorbent Assay
Viruses
Neutralization Tests
Chills
Sweating
Aedes
Myalgia
Hemagglutination
Back Pain
Nausea
Vomiting
Immunoglobulin M
Headache
Diarrhea
Mucous Membrane
Fever

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Nassar, E. S., Chamelet, E. L., Coimbra, T. L., de Souza, L. T., Suzuki, A., Ferreira, I. B., ... Travassos da Rosa, A. P. (1995). Jungle yellow fever: clinical and laboratorial studies emphasizing viremia on a human case. Revista do Instituto de Medicina Tropical de São Paulo, 37(4), 337-341.

Jungle yellow fever : clinical and laboratorial studies emphasizing viremia on a human case. / Nassar, E. S.; Chamelet, E. L.; Coimbra, T. L.; de Souza, L. T.; Suzuki, A.; Ferreira, I. B.; da Silva, M. V.; Rocco, I. M.; Travassos da Rosa, A. P.

In: Revista do Instituto de Medicina Tropical de São Paulo, Vol. 37, No. 4, 07.1995, p. 337-341.

Research output: Contribution to journalArticle

Nassar, ES, Chamelet, EL, Coimbra, TL, de Souza, LT, Suzuki, A, Ferreira, IB, da Silva, MV, Rocco, IM & Travassos da Rosa, AP 1995, 'Jungle yellow fever: clinical and laboratorial studies emphasizing viremia on a human case.', Revista do Instituto de Medicina Tropical de São Paulo, vol. 37, no. 4, pp. 337-341.
Nassar ES, Chamelet EL, Coimbra TL, de Souza LT, Suzuki A, Ferreira IB et al. Jungle yellow fever: clinical and laboratorial studies emphasizing viremia on a human case. Revista do Instituto de Medicina Tropical de São Paulo. 1995 Jul;37(4):337-341.
Nassar, E. S. ; Chamelet, E. L. ; Coimbra, T. L. ; de Souza, L. T. ; Suzuki, A. ; Ferreira, I. B. ; da Silva, M. V. ; Rocco, I. M. ; Travassos da Rosa, A. P. / Jungle yellow fever : clinical and laboratorial studies emphasizing viremia on a human case. In: Revista do Instituto de Medicina Tropical de São Paulo. 1995 ; Vol. 37, No. 4. pp. 337-341.
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