K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells

Keyphrases

• Colorectal Cancer 100%
• K-ras 100%
• Mutational Analysis 100%
• Circulating Tumor Cells 100%
• KRAS mutation 60%
• Codon 13 60%
• Colorectal Carcinoma 40%
• Tumor 40%
• Blood Samples 40%
• Aspartic Acid 40%
• Tumor Suppressor Gene 40%
• Oncogene 40%
• Codon 12 40%
• Primary Colorectal Cancer 40%
• Epithelial Cells 20%
• Specific mutation 20%
• Oncogenesis 20%
• Clinical Evidence 20%
• Peripheral Blood Mononuclear Cells 20%
• Exon 20%
• Molecular Analysis 20%
• Primary Lesion 20%
• Glycine 20%
• Divergence 20%
• Metastasizing 20%
• Before Surgery 20%
• Gel Electrophoresis 20%
• Multiple mutations 20%
• Primary Tumor 20%
• Curative Resection 20%
• Metastatic Lesions 20%
• Clonal Selection 20%
• Clonal Population 20%
• Circulating Cells 20%
• Whole Tumor 20%
• Mutational Patterns 20%
• Recurrent Cancer 20%
• Allele-specific Polymerase Chain Reaction 20%
• Microwell Array 20%
• Clonal Distribution 20%

Medicine and Dentistry

• Colorectal Carcinoma 100%
• Ras Signaling 100%
• Mutational Analysis 100%
• Circulating Tumor Cell 100%
• Codon 66%
• Neoplasm 50%
• Oncogene 33%
• Tumor Suppressor Gene 33%
• Aspartic Acid 33%
• Epithelial Cell 16%
• Carcinogenesis 16%
• Primary Tumor 16%
• Peripheral Blood Mononuclear Cell 16%
• Allele 16%
• Cancer Recurrence 16%
• Gel Electrophoresis 16%
• Oncogene Ras 16%
• Exon 16%
• Polymerase Chain Reaction 16%

Biochemistry, Genetics and Molecular Biology

• Codon 100%
• Oncogene 50%
• Tumor Suppressor Gene 50%
• Aspartic Acid 50%
• Carcinogenesis 25%
• Allele 25%
• Peripheral Blood Mononuclear Cell 25%
• Exon 25%
• Oncogene Ras 25%
• Clonal Population 25%
• Polymerase Chain Reaction 25%
• Gel Electrophoresis 25%