Karyotypic abnormalities and hydramnios

Role of amniocentesis

C. M. Zahn, Gary Hankins, E. R. Yeomans

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Hydramnios complicates up to 1.6% of pregnancies, with major fetal malformations found in an average of 20% of patients with hydramnios. Chromosomal abnormalities, although associated with some conditions in which hydramnios is present, have not been reported to complicate a significant percentage of hydramnios cases. Data from 45 patients admitted during the period January 1, 1985-May 31, 1990, were analyzed. All patients had hydramnios sufficiently severe to merit hospitalization for diagnosis and/or treatment. Amniocentesis was performed at the discretion of the attending physician and not under a specific protocol. The incidence of major fetal structural malformations was 36%. Of patients in whom amniocentesis was performed, 22% were found to have karyotypic abnormalities, none of which was specifically suspected prior to the amniocenteses. Neither the estimated gestational age nor the assessment of the amount of amniotic fluid differed between those with karyotypic abnormalities and those with normal chromosome complements. This information suggests that both advanced ultrasound studies and amniocentesis are beneficial in the evaluation of hydramnios.

Original languageEnglish (US)
Pages (from-to)599-602
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume38
Issue number8
StatePublished - 1993
Externally publishedYes

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Polyhydramnios
Amniocentesis
Amniotic Fluid
Chromosome Aberrations
Gestational Age
Hospitalization
Chromosomes
Physicians
Pregnancy
Incidence

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Karyotypic abnormalities and hydramnios : Role of amniocentesis. / Zahn, C. M.; Hankins, Gary; Yeomans, E. R.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 38, No. 8, 1993, p. 599-602.

Research output: Contribution to journalArticle

Zahn, C. M. ; Hankins, Gary ; Yeomans, E. R. / Karyotypic abnormalities and hydramnios : Role of amniocentesis. In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 1993 ; Vol. 38, No. 8. pp. 599-602.
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