Kinesin: possible biological roles for a new microtubule motor

Ronald D. Vale, Jonathan M. Scholey, Michael Sheetz

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Organelle transport along microtubules can be reconstituted using isolated components, allowing this complex motility process to be dissected biochemically. This approach has led to the purification of a novel and ubiquitous microtubule-based, force-generating protein named kinesin. The in vitro motile properties and immunocytochemical localization of kinesin suggest that it may serve as a motor for organelle transport and for microtubule-based movements during mitosis.

Original languageEnglish (US)
Pages (from-to)464-468
Number of pages5
JournalTrends in biochemical sciences
Volume11
Issue number11
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry

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