TY - JOUR
T1 - Kinesin
T2 - possible biological roles for a new microtubule motor
AU - Vale, Ronald D.
AU - Scholey, Jonathan M.
AU - Sheetz, Michael
PY - 1986/1/1
Y1 - 1986/1/1
N2 - Organelle transport along microtubules can be reconstituted using isolated components, allowing this complex motility process to be dissected biochemically. This approach has led to the purification of a novel and ubiquitous microtubule-based, force-generating protein named kinesin. The in vitro motile properties and immunocytochemical localization of kinesin suggest that it may serve as a motor for organelle transport and for microtubule-based movements during mitosis.
AB - Organelle transport along microtubules can be reconstituted using isolated components, allowing this complex motility process to be dissected biochemically. This approach has led to the purification of a novel and ubiquitous microtubule-based, force-generating protein named kinesin. The in vitro motile properties and immunocytochemical localization of kinesin suggest that it may serve as a motor for organelle transport and for microtubule-based movements during mitosis.
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U2 - 10.1016/0968-0004(86)90248-3
DO - 10.1016/0968-0004(86)90248-3
M3 - Article
AN - SCOPUS:0008801119
SN - 0968-0004
VL - 11
SP - 464
EP - 468
JO - Trends in biochemical sciences
JF - Trends in biochemical sciences
IS - 11
ER -