Kotonkan, a new rhabdovirus related to mokola virus of the rabies serogroup

Graham E. Kemp, Vernon H. Lee, Dorothy L. Moore, Robert E. Shope, Ottis R. Causey, Frederick A. Murphy

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Kotonkan virus (IbAr 23380), represented by a single isolate from Culicoides spp. collected at the University of Ibadan Agricultural Farm, Nigeria, in December 1967, is a chloroform-sensitive agent related to Mokola virus of the rabies serogroup by complement-fixation and fluorescent-antibody tests but not by neutralization test. Electron microscopic studies show the majority of virions to be cone-shaped like those of bovine ephemeral fever virus. Surveys of available serum specimens collected in Nigeria disclosed neutralizing substance for kotonkan virus in man, cattle, rodents and insectivores in the north, and in cattle, sheep and horses in the south. Results of additional neutralization tests with sera of newly imported cattle suffering a bovine ephemeral fever-like illness, suggest a possible connection between such outbreaks and kotonkan virus.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalAmerican journal of epidemiology
Issue number1
StatePublished - Jul 1973


  • Complement-fixation test
  • Culicoides
  • Fluorescent-antibody test
  • Kotonkan virus
  • Mokola virus
  • Neutralization test
  • Rabies serogroup
  • Rhabdovirus

ASJC Scopus subject areas

  • Epidemiology


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