L-Threodops increases extracellular norepinephrine levels in the brain: An in vivo study

Timothy Brannan, Anish Bhardwaj, Melvin D. Yahr

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Extracellular norepinephrine levels in the striatum of normal rats increased significantly following the administration of L-threodops. When peripheral decarboxylase activity was inhibited with carbidopa, administration of the same dose of L-threodops induced a 2.5-fold greater increase in norepinephrine levels.

Original languageEnglish (US)
Pages (from-to)1134-1135
Number of pages2
JournalNeurology
Volume40
Issue number7
StatePublished - Jul 1990
Externally publishedYes

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ASJC Scopus subject areas

  • Neuroscience(all)

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