Laboratory studies of transovarial transmission of La Crosse and other arboviruses by Aedes albopictus and Culex fatigans

R. B. Tesh, D. J. Gubler

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Transovarial transmission of La Crosse virus by experimentally infected Aedes albopictus females to 2.7% of their F1 generation offspring was demonstrated. Progeny of both sexes were infected. Mean virus titers in parent mosquitoes and infected F1 generation adults were 10(superior 4.6) and 10(superior 3.4) plaque forming units/insect, respectively. The La Crosse infected offspring were randomly distributed among the female parents. After 2 serial passages in A. albopictus, a marked change occurred in the plaque morphology of the virus but this had no apparent effect on the subsequent vertical transmission rate. In contrast, transovarial transmission did not occur in La Crosse infected Culex fatigans or in A. albopictus and C. fatigans infected with vesicular stomatitis Indiana, Cache Valley, Batai, Arumowot, and Itaporanga viruses. Results of this experiment suggest that the La Crosse model might be useful in studying the mechanism of transovarial transmission in additional mosquito species.

Original languageEnglish (US)
Pages (from-to)876-880
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume24
Issue number5
DOIs
StatePublished - Jan 1 1975

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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