Laser optoacoustic technique for real-time measurement of thermal damage in tissues

Rinat Esenaliev, Irina Larina, Kirill Larin, Massoud Motamedi, Alexander Karabutov, Alexander Oraevsky

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Citations (Scopus)

Abstract

Optoacoustic monitoring of thermally-induced damage in tissues in real time is proposed as a mean for controlling the extent of tissue coagulation in human organs, such as liver, prostate, myocardium, breast, and brain. This technique can potentially provide fast and accurate feedback information during tumor thermal coagulation by interstitial delivery of laser, ultrasonic, radiofrequency, and microwave radiation or conductive and convective heating. Amplitude and temporal characteristics of optoacoustic signals are dependent on optical and thermophysical properties of tissues. Changes in tissue optical properties during coagulation can be detected by measuring and analyzing the amplitude and temporal characteristics of the optoacoustic signals. We performed studies on optoacoustic monitoring of coagulation by CW Nd:YAG laser interstitial irradiation and conductive heating. Q-switched Nd:YAG laser pulses were used as a probing radiation to obtain optoacoustic pressure profiles and images. Our preliminary studies suggest that the laser optoacoustic technique is capable of detecting thermally-induced changes in optical properties of liver, myocardium, and prostate. The major merits of the laser opto-acoustic monitoring of tissue coagulation include high contrast provided by changes in tissue optical properties, capability to perform real-time measurements, and high spatial resolution.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages98-109
Number of pages12
Volume3594
StatePublished - 1999
EventProceedings of the 1999 Thermal Treatment of Tissue with Image Guidance - San Jose, CA, USA
Duration: Jan 24 1999Jan 25 1999

Other

OtherProceedings of the 1999 Thermal Treatment of Tissue with Image Guidance
CitySan Jose, CA, USA
Period1/24/991/25/99

Fingerprint

Photoacoustic effect
Time measurement
coagulation
Coagulation
time measurement
Tissue
damage
Lasers
Optical properties
lasers
optical properties
myocardium
liver
Liver
YAG lasers
Monitoring
interstitials
Heating
heating
thermophysical properties

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Esenaliev, R., Larina, I., Larin, K., Motamedi, M., Karabutov, A., & Oraevsky, A. (1999). Laser optoacoustic technique for real-time measurement of thermal damage in tissues. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3594, pp. 98-109). Society of Photo-Optical Instrumentation Engineers.

Laser optoacoustic technique for real-time measurement of thermal damage in tissues. / Esenaliev, Rinat; Larina, Irina; Larin, Kirill; Motamedi, Massoud; Karabutov, Alexander; Oraevsky, Alexander.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3594 Society of Photo-Optical Instrumentation Engineers, 1999. p. 98-109.

Research output: Chapter in Book/Report/Conference proceedingChapter

Esenaliev, R, Larina, I, Larin, K, Motamedi, M, Karabutov, A & Oraevsky, A 1999, Laser optoacoustic technique for real-time measurement of thermal damage in tissues. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3594, Society of Photo-Optical Instrumentation Engineers, pp. 98-109, Proceedings of the 1999 Thermal Treatment of Tissue with Image Guidance, San Jose, CA, USA, 1/24/99.
Esenaliev R, Larina I, Larin K, Motamedi M, Karabutov A, Oraevsky A. Laser optoacoustic technique for real-time measurement of thermal damage in tissues. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3594. Society of Photo-Optical Instrumentation Engineers. 1999. p. 98-109
Esenaliev, Rinat ; Larina, Irina ; Larin, Kirill ; Motamedi, Massoud ; Karabutov, Alexander ; Oraevsky, Alexander. / Laser optoacoustic technique for real-time measurement of thermal damage in tissues. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3594 Society of Photo-Optical Instrumentation Engineers, 1999. pp. 98-109
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