Laser optoacoustic tomography of layered tissues

Signal processing

Alexander A. Oraevsky, Rinat Esenaliev, Alexander Karabutov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

22 Citations (Scopus)

Abstract

Laser optoacoustic imaging experiments in biological tissues in vivo are presented along with the theoretical signal analysis procedure. The laser optoacoustic imaging system (LOIS) can operate in the reflection mode with emphasis on high z-axial (in-depth) resolution (up to 10-20 μm). Two examples of LOIS applications for non-invasive in vivo medical diagnostics are presented and discussed: (1) characterization of layered structure of port-wine stains, and (2) measurements of skin melanoma thickness. Potential miniaturization of LOIS for endoscopy applications is also discussed. The z-axial profiles of laser-induced pressure were shown to contain diagnostic information on location, dimensions and optical properties of tissue layers. Time-resolved signals detected by piezoelectric transducers were corrected for distortions such as diffraction and acoustic attenuation that occur upon pressure wave propagation in tissue. Wavelet transform applied to signals of laser-induced acoustic emission yielded high contrast pressure profiles with substantial signal-to-noise ratio.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsB. Chance, R.R. Alfano, A. Katzir
Pages59-70
Number of pages12
Volume2979
DOIs
StatePublished - 1997
Externally publishedYes
EventProceedings of Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model and Human Studies II - San Jose, CA, United States
Duration: Feb 9 1997Feb 12 1997

Other

OtherProceedings of Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model and Human Studies II
CountryUnited States
CitySan Jose, CA
Period2/9/972/12/97

Fingerprint

Photoacoustic effect
Tomography
signal processing
Signal processing
tomography
Tissue
Lasers
Imaging systems
lasers
wines
acoustic attenuation
Piezoelectric transducers
Endoscopy
time signals
Wine
signal analysis
piezoelectric transducers
Signal analysis
acoustic emission
miniaturization

Keywords

  • Absorbed energy distribution
  • Conditions of temporal stress confinement
  • Imaging
  • Laser-induced pressure
  • Piezoelectric transducer
  • Transient stress

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Oraevsky, A. A., Esenaliev, R., & Karabutov, A. (1997). Laser optoacoustic tomography of layered tissues: Signal processing. In B. Chance, R. R. Alfano, & A. Katzir (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2979, pp. 59-70) https://doi.org/10.1117/12.280297

Laser optoacoustic tomography of layered tissues : Signal processing. / Oraevsky, Alexander A.; Esenaliev, Rinat; Karabutov, Alexander.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / B. Chance; R.R. Alfano; A. Katzir. Vol. 2979 1997. p. 59-70.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oraevsky, AA, Esenaliev, R & Karabutov, A 1997, Laser optoacoustic tomography of layered tissues: Signal processing. in B Chance, RR Alfano & A Katzir (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2979, pp. 59-70, Proceedings of Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model and Human Studies II, San Jose, CA, United States, 2/9/97. https://doi.org/10.1117/12.280297
Oraevsky AA, Esenaliev R, Karabutov A. Laser optoacoustic tomography of layered tissues: Signal processing. In Chance B, Alfano RR, Katzir A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2979. 1997. p. 59-70 https://doi.org/10.1117/12.280297
Oraevsky, Alexander A. ; Esenaliev, Rinat ; Karabutov, Alexander. / Laser optoacoustic tomography of layered tissues : Signal processing. Proceedings of SPIE - The International Society for Optical Engineering. editor / B. Chance ; R.R. Alfano ; A. Katzir. Vol. 2979 1997. pp. 59-70
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