Late pancreas retransplantation

Jonathan A. Fridell, Richard S. Mangus, Jeanne M. Chen, Michelle L. Goble, Muhammad Mujtaba, Tim E. Taber, John A. Powelson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Pancreas retransplantation, excluding immediate retransplantation for graft thrombosis, is a technically treacherous operation with the added challenges of adhesions from the prior transplant and difficulties identifying usable recipient vessels. The goal of this study was to review our single-center experience with late pancreas retransplantation. Charts for all pancreas transplant recipients between 01/2003 and 04/2013 were reviewed for demographics, graft and patient survival, length of stay (LOS), readmissions, and technical complications. Of 473 pancreas transplants, there were 20 late pancreas retransplants compared to 441 first transplants. There were no significant differences in donor or recipient demographics. There was no significant difference in graft or patient survival. The mean and median lengths of stay were 22 and nine d, respectively (range 5-175 d), and 11 recipients required readmission within the first three months post-transplant. Five patients were reexplored in the early postoperative period for an enteric leak at the site of the primary allograft (n = 1), complications of percutaneous gastrostomy tube placement (n = 1), hemorrhage (n = 1), and negative laparotomy for hyperglycemia (n = 2). Pancreas retransplantation is technically challenging but can be safely performed with graft and recipient survival comparable to primary transplants.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalClinical Transplantation
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

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Keywords

  • Chronic rejection
  • Pancreas transplantation
  • Retransplantation
  • Simultaneous pancreas and kidney transplantation
  • Technical complications

ASJC Scopus subject areas

  • Transplantation

Cite this

Fridell, J. A., Mangus, R. S., Chen, J. M., Goble, M. L., Mujtaba, M., Taber, T. E., & Powelson, J. A. (2015). Late pancreas retransplantation. Clinical Transplantation, 29(1), 1-8. https://doi.org/10.1111/ctr.12468