Lateral membrane waves constitute a universal dynamic pattern of motile cells

Hans Günther Döbereiner, Benjamin J. Dubin-Thaler, Jake M. Hofman, Harry S. Xenias, Tasha N. Sims, Grégory Giannone, Michael L. Dustin, Chris H. Wiggins, Michael Sheetz

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

We have monitored active movements of the cell circumference on specifically coated substrates for a variety of cells including mouse embryonic fibroblasts and T cells, as well as wing disk cells from fruit flies. Despite having different functions and being from multiple phyla, these cell types share a common spatiotemporal pattern in their normal membrane velocity; we show that protrusion and retraction events are organized in lateral waves along the cell membrane. These wave patterns indicate both spatial and temporal long-range periodic correlations of the actomyosin gel.

Original languageEnglish (US)
Article number038102
JournalPhysical Review Letters
Volume97
Issue number3
DOIs
StatePublished - Jul 27 2006
Externally publishedYes

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membranes
cells
fruits
circumferences
fibroblasts
wings
mice
gels

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Döbereiner, H. G., Dubin-Thaler, B. J., Hofman, J. M., Xenias, H. S., Sims, T. N., Giannone, G., ... Sheetz, M. (2006). Lateral membrane waves constitute a universal dynamic pattern of motile cells. Physical Review Letters, 97(3), [038102]. https://doi.org/10.1103/PhysRevLett.97.038102

Lateral membrane waves constitute a universal dynamic pattern of motile cells. / Döbereiner, Hans Günther; Dubin-Thaler, Benjamin J.; Hofman, Jake M.; Xenias, Harry S.; Sims, Tasha N.; Giannone, Grégory; Dustin, Michael L.; Wiggins, Chris H.; Sheetz, Michael.

In: Physical Review Letters, Vol. 97, No. 3, 038102, 27.07.2006.

Research output: Contribution to journalArticle

Döbereiner, HG, Dubin-Thaler, BJ, Hofman, JM, Xenias, HS, Sims, TN, Giannone, G, Dustin, ML, Wiggins, CH & Sheetz, M 2006, 'Lateral membrane waves constitute a universal dynamic pattern of motile cells', Physical Review Letters, vol. 97, no. 3, 038102. https://doi.org/10.1103/PhysRevLett.97.038102
Döbereiner HG, Dubin-Thaler BJ, Hofman JM, Xenias HS, Sims TN, Giannone G et al. Lateral membrane waves constitute a universal dynamic pattern of motile cells. Physical Review Letters. 2006 Jul 27;97(3). 038102. https://doi.org/10.1103/PhysRevLett.97.038102
Döbereiner, Hans Günther ; Dubin-Thaler, Benjamin J. ; Hofman, Jake M. ; Xenias, Harry S. ; Sims, Tasha N. ; Giannone, Grégory ; Dustin, Michael L. ; Wiggins, Chris H. ; Sheetz, Michael. / Lateral membrane waves constitute a universal dynamic pattern of motile cells. In: Physical Review Letters. 2006 ; Vol. 97, No. 3.
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