Lateralization discordance between stereo EEG and scalp EEG in temporal epilepsy: A case report

Spencer Gunnell; Audrey Nath; Patrick Karas; Todd Masel

doi:10.1016/j.ebr.2025.100803

Lateralization discordance between stereo EEG and scalp EEG in temporal epilepsy: A case report

Spencer Gunnell, Audrey Nath, Patrick Karas, Todd Masel

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A 34-year-old woman with drug-resistant epilepsy underwent simultaneous scalp and stereo-EEG (sEEG) and had seven seizures, three of them without visibility on the scalp EEG. Of the four seizures seen on both sEEG and scalp EEG, the seizure onset in the scalp EEG was ipsilateral to the seizure onset in the sEEG in two seizures and contralateral to the sEEG onset in two seizures. This unusual lateralization discordance of scalp EEG and sEEG highlights the importance of bilateral lead placement in stereo EEG to accurately identify the seizure onset zone.

Original language	English (US)
Article number	100803
Journal	Epilepsy and Behavior Reports
Volume	31
DOIs	https://doi.org/10.1016/j.ebr.2025.100803
State	Published - Sep 2025

Keywords

Discordance
Lateralization
Refractory Epilepsy
Scalp EEG
Stereo-EEG

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.ebr.2025.100803

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title = "Lateralization discordance between stereo EEG and scalp EEG in temporal epilepsy: A case report",

abstract = "A 34-year-old woman with drug-resistant epilepsy underwent simultaneous scalp and stereo-EEG (sEEG) and had seven seizures, three of them without visibility on the scalp EEG. Of the four seizures seen on both sEEG and scalp EEG, the seizure onset in the scalp EEG was ipsilateral to the seizure onset in the sEEG in two seizures and contralateral to the sEEG onset in two seizures. This unusual lateralization discordance of scalp EEG and sEEG highlights the importance of bilateral lead placement in stereo EEG to accurately identify the seizure onset zone.",

keywords = "Discordance, Lateralization, Refractory Epilepsy, Scalp EEG, Stereo-EEG",

author = "Spencer Gunnell and Audrey Nath and Patrick Karas and Todd Masel",

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year = "2025",

month = sep,

doi = "10.1016/j.ebr.2025.100803",

language = "English (US)",

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journal = "Epilepsy and Behavior Reports",

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T1 - Lateralization discordance between stereo EEG and scalp EEG in temporal epilepsy

T2 - A case report

AU - Gunnell, Spencer

AU - Nath, Audrey

AU - Karas, Patrick

AU - Masel, Todd

PY - 2025/9

Y1 - 2025/9

N2 - A 34-year-old woman with drug-resistant epilepsy underwent simultaneous scalp and stereo-EEG (sEEG) and had seven seizures, three of them without visibility on the scalp EEG. Of the four seizures seen on both sEEG and scalp EEG, the seizure onset in the scalp EEG was ipsilateral to the seizure onset in the sEEG in two seizures and contralateral to the sEEG onset in two seizures. This unusual lateralization discordance of scalp EEG and sEEG highlights the importance of bilateral lead placement in stereo EEG to accurately identify the seizure onset zone.

AB - A 34-year-old woman with drug-resistant epilepsy underwent simultaneous scalp and stereo-EEG (sEEG) and had seven seizures, three of them without visibility on the scalp EEG. Of the four seizures seen on both sEEG and scalp EEG, the seizure onset in the scalp EEG was ipsilateral to the seizure onset in the sEEG in two seizures and contralateral to the sEEG onset in two seizures. This unusual lateralization discordance of scalp EEG and sEEG highlights the importance of bilateral lead placement in stereo EEG to accurately identify the seizure onset zone.

KW - Discordance

KW - Lateralization

KW - Refractory Epilepsy

KW - Scalp EEG

KW - Stereo-EEG

UR - https://www.scopus.com/pages/publications/105009765175

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DO - 10.1016/j.ebr.2025.100803

M3 - Article

C2 - 40688009

AN - SCOPUS:105009765175

SN - 2213-3232

VL - 31

JO - Epilepsy and Behavior Reports

JF - Epilepsy and Behavior Reports

M1 - 100803

ER -

Lateralization discordance between stereo EEG and scalp EEG in temporal epilepsy: A case report

Abstract

Keywords

ASJC Scopus subject areas

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