Lead Poisoning in an Art Conservator

Alf Fischbein, Joyce Wallace, Karl Anderson, Shigeru Sassa, Steven Kon, Arthur N. Rohl, Attallah Kappas

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A case of lead poisoning in a female art conservator is reported. The patient had experienced excessive lead exposure while restoring an antique Peruvian tapestry from the Chancay period (1000 to 1500 AD) using a powdered pigment (cinnabar), which had been recovered from the same tomb in which the tapestry was found. Over two months, prominent neurological, gastrointestinal, and diffuse muscular symptoms developed. Severe anemia accompanied by basophilic stippling of RBCs led to the diagnosis of lead poisoning, which was confirmed by markedly elevated blood lead levels (up to 130 μg/dL) and impairment of heme synthetic enzymes. The severity of the intoxication necessitated chelation therapy. Chemical analysis of the antique powdered pigment showed it to be the source of lead exposure, in that it contained about 1% lead.

Original languageEnglish (US)
Pages (from-to)2007-2009
Number of pages3
JournalJAMA - Journal of the American Medical Association
Volume247
Issue number14
DOIs
StatePublished - Apr 9 1982
Externally publishedYes

Fingerprint

Lead Poisoning
Art
Chelation Therapy
Heme
Anemia
Lead
Enzymes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fischbein, A., Wallace, J., Anderson, K., Sassa, S., Kon, S., Rohl, A. N., & Kappas, A. (1982). Lead Poisoning in an Art Conservator. JAMA - Journal of the American Medical Association, 247(14), 2007-2009. https://doi.org/10.1001/jama.1982.03320390069049

Lead Poisoning in an Art Conservator. / Fischbein, Alf; Wallace, Joyce; Anderson, Karl; Sassa, Shigeru; Kon, Steven; Rohl, Arthur N.; Kappas, Attallah.

In: JAMA - Journal of the American Medical Association, Vol. 247, No. 14, 09.04.1982, p. 2007-2009.

Research output: Contribution to journalArticle

Fischbein, A, Wallace, J, Anderson, K, Sassa, S, Kon, S, Rohl, AN & Kappas, A 1982, 'Lead Poisoning in an Art Conservator', JAMA - Journal of the American Medical Association, vol. 247, no. 14, pp. 2007-2009. https://doi.org/10.1001/jama.1982.03320390069049
Fischbein, Alf ; Wallace, Joyce ; Anderson, Karl ; Sassa, Shigeru ; Kon, Steven ; Rohl, Arthur N. ; Kappas, Attallah. / Lead Poisoning in an Art Conservator. In: JAMA - Journal of the American Medical Association. 1982 ; Vol. 247, No. 14. pp. 2007-2009.
@article{363f81568b40441a9961f41f7f7e3f2c,
title = "Lead Poisoning in an Art Conservator",
abstract = "A case of lead poisoning in a female art conservator is reported. The patient had experienced excessive lead exposure while restoring an antique Peruvian tapestry from the Chancay period (1000 to 1500 AD) using a powdered pigment (cinnabar), which had been recovered from the same tomb in which the tapestry was found. Over two months, prominent neurological, gastrointestinal, and diffuse muscular symptoms developed. Severe anemia accompanied by basophilic stippling of RBCs led to the diagnosis of lead poisoning, which was confirmed by markedly elevated blood lead levels (up to 130 μg/dL) and impairment of heme synthetic enzymes. The severity of the intoxication necessitated chelation therapy. Chemical analysis of the antique powdered pigment showed it to be the source of lead exposure, in that it contained about 1{\%} lead.",
author = "Alf Fischbein and Joyce Wallace and Karl Anderson and Shigeru Sassa and Steven Kon and Rohl, {Arthur N.} and Attallah Kappas",
year = "1982",
month = "4",
day = "9",
doi = "10.1001/jama.1982.03320390069049",
language = "English (US)",
volume = "247",
pages = "2007--2009",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "14",

}

TY - JOUR

T1 - Lead Poisoning in an Art Conservator

AU - Fischbein, Alf

AU - Wallace, Joyce

AU - Anderson, Karl

AU - Sassa, Shigeru

AU - Kon, Steven

AU - Rohl, Arthur N.

AU - Kappas, Attallah

PY - 1982/4/9

Y1 - 1982/4/9

N2 - A case of lead poisoning in a female art conservator is reported. The patient had experienced excessive lead exposure while restoring an antique Peruvian tapestry from the Chancay period (1000 to 1500 AD) using a powdered pigment (cinnabar), which had been recovered from the same tomb in which the tapestry was found. Over two months, prominent neurological, gastrointestinal, and diffuse muscular symptoms developed. Severe anemia accompanied by basophilic stippling of RBCs led to the diagnosis of lead poisoning, which was confirmed by markedly elevated blood lead levels (up to 130 μg/dL) and impairment of heme synthetic enzymes. The severity of the intoxication necessitated chelation therapy. Chemical analysis of the antique powdered pigment showed it to be the source of lead exposure, in that it contained about 1% lead.

AB - A case of lead poisoning in a female art conservator is reported. The patient had experienced excessive lead exposure while restoring an antique Peruvian tapestry from the Chancay period (1000 to 1500 AD) using a powdered pigment (cinnabar), which had been recovered from the same tomb in which the tapestry was found. Over two months, prominent neurological, gastrointestinal, and diffuse muscular symptoms developed. Severe anemia accompanied by basophilic stippling of RBCs led to the diagnosis of lead poisoning, which was confirmed by markedly elevated blood lead levels (up to 130 μg/dL) and impairment of heme synthetic enzymes. The severity of the intoxication necessitated chelation therapy. Chemical analysis of the antique powdered pigment showed it to be the source of lead exposure, in that it contained about 1% lead.

UR - http://www.scopus.com/inward/record.url?scp=84944369577&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944369577&partnerID=8YFLogxK

U2 - 10.1001/jama.1982.03320390069049

DO - 10.1001/jama.1982.03320390069049

M3 - Article

C2 - 7062508

AN - SCOPUS:84944369577

VL - 247

SP - 2007

EP - 2009

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 14

ER -