Left ventricular mass changes associated with metabolic syndrome in hispanics

Sarmad Said, Haider Alkhateeb, Chad J. Cooper, Carlos E. Rodriguez-Castro, Alok Dwivedi, Emmanuel Rodriguez, Remi Trien, Juan M. Galvis, Maryna J. Popp-Switzer, Jiayang Liu, Hongfei Fang, Rahul Chhana, Debabrata Mukherjee

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Metabolic syndrome (MeS) is linked with risk for cardiovascular disease. Prevalence of cardiovascular disease in Hispanics is higher compared with other groups. Few data are available comparing components of MeS on left ventricular mass (LVM). Retrospective analysis was conducted on subjects with (N=1089) and without MeS (N=118), who had previous echocardiography (55.92% male, aged 54.59±9.89). LVM was compared with the presence or absence of MeS components. LVM was higher in the group with ≥ 3 components (198.78g. P<0.0001). Lower high-density-lipoprotein, increased blood pressure, increased fasting-serum-glucose and obesity were associated with higher LVM. No difference was noted in Hispanics vs. other groups. Individuals with ≥ 3 components were found to have more impact on LVM compared to those with 1-2 components (P0.0034). Caucasian had less increase in the LVM-Index vs. Hispanics (P0.0289). The results of this report demonstrate an association between MeS components and LVM in predominantly Hispanic-community. This link of higher LVM and LVM-Index is strong among females. Hypertension, dyslipidemia, higher body-mass-index, diabetes, and advanced age have a strong influence on LVM. The prognostic significance of LVM in subjects with MeS requires further investigation, particularly in ethnic minority groups.

Original languageEnglish (US)
Pages (from-to)3086-3099
Number of pages14
JournalExperimental and Clinical Cardiology
Issue number5
StatePublished - 2014
Externally publishedYes


  • Left ventricular mass
  • Left ventricular mass index
  • Metabolic syndrome
  • Relative wall thickness

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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