Leishmania amazonensis: Sensitivity of different promastigote morphotypes to salivary gland homogenates of the sand fly lutzomyia longipalpis

Rosane Charlab, José M.C. Ribeiro, Robert B. Tesh, Edgar D. Rowton

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

We have recently demonstrated that Luizomyia longipalpis salivary gland homogenates (SGH) inhibited the multiplication of Leishmania promastigotes in vitro. The present work shows that Leishmania amazonensis sensitivity to SGH is correlated to the phase of promastigote in vitro growth and can be decreased by the addition of hemin to the culture medium. The possible relevance of these in vitro results is discussed in relation to the development of Leishmania parasites within their sand fly vectors.

Original languageEnglish (US)
Article number71021
Pages (from-to)167-175
Number of pages9
JournalExperimental Parasitology
Volume80
Issue number2
DOIs
StatePublished - Mar 1995

ASJC Scopus subject areas

  • Parasitology
  • Immunology
  • Infectious Diseases

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