Leishmania amazonensis: Sensitivity of Different Promastigote Morphotypes to Salivary Gland Homogenates of the Sand Fly Lutzomyia longipalpis

R. Charlab, R. B. Tesh, E. D. Rowton, J. M C Ribeiro

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We have recently demonstrated that Luizomyia longipalpis salivary gland homogenates (SGH) inhibited the multiplication of Leishmania promastigotes in vitro. The present work shows that Leishmania amazonensis sensitivity to SGH is correlated to the phase of promastigote in vitro growth and can be decreased by the addition of hemin to the culture medium. The possible relevance of these in vitro results is discussed in relation to the development of Leishmania parasites within their sand fly vectors.

Original languageEnglish (US)
Pages (from-to)167-175
Number of pages9
JournalExperimental Parasitology
Volume80
Issue number2
DOIs
StatePublished - Mar 1995
Externally publishedYes

Fingerprint

Psychodidae
Leishmania
Salivary Glands
Hemin
Culture Media
Parasites
Growth
In Vitro Techniques

ASJC Scopus subject areas

  • Parasitology
  • Immunology
  • Infectious Diseases

Cite this

Leishmania amazonensis : Sensitivity of Different Promastigote Morphotypes to Salivary Gland Homogenates of the Sand Fly Lutzomyia longipalpis. / Charlab, R.; Tesh, R. B.; Rowton, E. D.; Ribeiro, J. M C.

In: Experimental Parasitology, Vol. 80, No. 2, 03.1995, p. 167-175.

Research output: Contribution to journalArticle

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