Abstract
Leishmania parasites are transmitted by phlebotomine sand flies and can cause diverse clinical manifestations known as leishmaniasis. Drug resistance/toxicity and Leishmania/HIV coinfection call for a safe, effective vaccine. Recent research focuses on generating vaccines targeted on parasite- or sand fly-derived components. Defining the optimal combinations of antigens and adjuvants that elicit durable cellular immunity is critical for the control of leishmaniasis.
Original language | English (US) |
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Title of host publication | Vaccines for Biodefense and Emerging and Neglected Diseases |
Publisher | Elsevier Inc. |
Pages | 1275-1289 |
Number of pages | 15 |
ISBN (Print) | 9780123694089 |
DOIs | |
State | Published - 2009 |
ASJC Scopus subject areas
- General Immunology and Microbiology