Leishmania parasites are transmitted by phlebotomine sand flies and can cause diverse clinical manifestations known as leishmaniasis. Drug resistance/toxicity and Leishmania/HIV coinfection call for a safe, effective vaccine. Recent research focuses on generating vaccines targeted on parasite- or sand fly-derived components. Defining the optimal combinations of antigens and adjuvants that elicit durable cellular immunity is critical for the control of leishmaniasis.
|Original language||English (US)|
|Title of host publication||Vaccines for Biodefense and Emerging and Neglected Diseases|
|Number of pages||15|
|State||Published - Jan 1 2008|
ASJC Scopus subject areas
- Immunology and Microbiology(all)