Abstract
Leishmania parasites are transmitted by phlebotomine sand flies and can cause diverse clinical manifestations known as leishmaniasis. Drug resistance/toxicity and Leishmania/HIV coinfection call for a safe, effective vaccine. Recent research focuses on generating vaccines targeted on parasite- or sand fly-derived components. Defining the optimal combinations of antigens and adjuvants that elicit durable cellular immunity is critical for the control of leishmaniasis.
| Original language | English (US) |
|---|---|
| Title of host publication | Vaccines for Biodefense and Emerging and Neglected Diseases |
| Publisher | Elsevier Inc. |
| Pages | 1275-1289 |
| Number of pages | 15 |
| ISBN (Print) | 9780123694089 |
| DOIs | |
| State | Published - 2009 |
ASJC Scopus subject areas
- General Immunology and Microbiology