Length of latency with preterm premature rupture of membranes before 32 weeks' gestation

Alan M. Peaceman, Yinglei Lai, Dwight J. Rouse, Catherine Y. Spong, Brian M. Mercer, Michael W. Varner, John M. Thorp, Susan M. Ramin, Fergal D. Malone, Mary J. O'Sullivan, Gary Hankins

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

OBJECTIVE: The objective of the article is to describe latency for patients with preterm premature membrane rupture (PPROM) between 24(0/7) and 31(6/7) weeks' gestation.

STUDY DESIGN: Secondary analysis of data collected prospectively in a multicenter clinical trial of magnesium sulfate for cerebral palsy prevention. Women with PPROM and fewer than six contractions per hour at enrollment who were candidates for expectant management (n = 1,377) were included in this analysis. Length of latency was calculated in days by subtracting the time of delivery from the time of membrane rupture.

RESULTS: At each week of gestation, median latency between 24 and 28 weeks was similar at approximately 9 days, but it was significantly shorter with PPROM at 29, 30, and 31 weeks (p 

CONCLUSION: Median latency after PPROM is similar from 24 to 28 weeks' gestation, but it shortens with PPROM at and after 29 weeks.

Original languageEnglish (US)
Pages (from-to)57-62
Number of pages6
JournalAmerican Journal of Perinatology
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2015

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Pregnancy
Magnesium Sulfate
Cerebral Palsy
Multicenter Studies
Preterm Premature Rupture of the Membranes
Rupture
Clinical Trials
Membranes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Peaceman, A. M., Lai, Y., Rouse, D. J., Spong, C. Y., Mercer, B. M., Varner, M. W., ... Hankins, G. (2015). Length of latency with preterm premature rupture of membranes before 32 weeks' gestation. American Journal of Perinatology, 32(1), 57-62. https://doi.org/10.1055/s-0034-1373846

Length of latency with preterm premature rupture of membranes before 32 weeks' gestation. / Peaceman, Alan M.; Lai, Yinglei; Rouse, Dwight J.; Spong, Catherine Y.; Mercer, Brian M.; Varner, Michael W.; Thorp, John M.; Ramin, Susan M.; Malone, Fergal D.; O'Sullivan, Mary J.; Hankins, Gary.

In: American Journal of Perinatology, Vol. 32, No. 1, 01.01.2015, p. 57-62.

Research output: Contribution to journalArticle

Peaceman, AM, Lai, Y, Rouse, DJ, Spong, CY, Mercer, BM, Varner, MW, Thorp, JM, Ramin, SM, Malone, FD, O'Sullivan, MJ & Hankins, G 2015, 'Length of latency with preterm premature rupture of membranes before 32 weeks' gestation', American Journal of Perinatology, vol. 32, no. 1, pp. 57-62. https://doi.org/10.1055/s-0034-1373846
Peaceman, Alan M. ; Lai, Yinglei ; Rouse, Dwight J. ; Spong, Catherine Y. ; Mercer, Brian M. ; Varner, Michael W. ; Thorp, John M. ; Ramin, Susan M. ; Malone, Fergal D. ; O'Sullivan, Mary J. ; Hankins, Gary. / Length of latency with preterm premature rupture of membranes before 32 weeks' gestation. In: American Journal of Perinatology. 2015 ; Vol. 32, No. 1. pp. 57-62.
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AU - Varner, Michael W.

AU - Thorp, John M.

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