Lethality in yeast of trichothiodystrophy (TTD) mutations in the human xeroderma pigmentosum group D gene. Implications for transcriptional defect in TTD

Medicine & Life Sciences

• Aptitude 5%
• DNA 4%
• DNA Helicases 23%
• DNA Repair 15%
• Genes 23%
• Hair 8%
• Ichthyosis 11%
• Intellectual Disability 7%
• Loss of Function Mutation 28%
• Mutant Proteins 9%
• Mutation 33%
• Neoplasms 2%
• Proteins 9%
• RNA Polymerase II 19%
• Saccharomyces cerevisiae 15%
• Sulfur 9%
• Trichothiodystrophy Syndromes 100%
• Xeroderma Pigmentosum 79%
• Yeasts 47%

Chemical Compounds

• Mutation 50%
• Nucleotide 9%
• Protein 9%