Letter: Localized cutaneous reaction to intramuscular vitamin K in a patient with acute fatty liver of pregnancy

Tatiana Sousa, Lindsey Hunter, Matthew Petitt, Michael Wilkerson

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3 Scopus citations


Vitamin K1 is frequently used in the treatment and prevention of hypoprothrombinemia and hemorrhagic disease of the newborn. It also serves as an antidote to anticoagulants. Erythematous, indurated, pruritic plaques uncommonly occur in adults after intramuscular injection with vitamin K1. We present a case of a localized cutaneous reaction to intramuscular vitamin K1 in a peripartum patient with acute fatty liver of pregnancy. The history and clinical presentation of our case is presented with a discussion of the pathogenesis pathogenesis of vitamin K1 and available treatment for this condition.

Original languageEnglish (US)
Pages (from-to)16
Number of pages1
JournalDermatology Online Journal
Issue number12
StatePublished - Dec 2010


ASJC Scopus subject areas

  • Dermatology

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