Lighting the way to host-directed immunotherapeutics

Sarah van Tol, Adam Hage, Ricardo Rajsbaum Gorodezky

Research output: Contribution to journalComment/debatepeer-review

Abstract

Developing broad-spectrum, host-directed antiviral therapeutics can be adapted to combat emerging viruses. In this issue of Cell Chemical Biology, Maarifi and colleagues implement a Nano luciferase reporter-based protein complementation assay to screen for small molecules and identify Gilteritinib, which enhances interferon induction and antagonizes virus replication.

Original languageEnglish (US)
Pages (from-to)1067-1070
Number of pages4
JournalCell Chemical Biology
Volume29
Issue number7
DOIs
StatePublished - Jul 21 2022

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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