Limb salvage using preoperative intraarterial adriamycin and radiation therapy for extremity soft tissue sarcomas

D. L. Morton, F. R. Eilber, T. H. Weisenburger, Courtney Townsend, J. M. Mirra

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Surgical therapy has been the accepted method for management of most soft tissue sarcomas of the extremities, although it has been associated frequently with local treatment failure. Even when local control was achieved, over 50% of the patients with soft tissue sarcomas eventually developed and succumbed to distant metastases of their disease. Therefore, single modality therapy for soft tissue sarcomas by operation alone results in an unacceptably high incidence of treatment failure. Fortunately, new adjuvant treatment techniques have been developed that seem to have activity against these neoplasms. It is the purpose of this article to discuss our experience with a number of these techniques.

Original languageEnglish (US)
Pages (from-to)56-59
Number of pages4
JournalAustralian and New Zealand Journal of Surgery
Volume48
Issue number1
StatePublished - 1978
Externally publishedYes

Fingerprint

Limb Salvage
Sarcoma
Doxorubicin
Radiotherapy
Extremities
Treatment Failure
Therapeutics
Neoplasm Metastasis
Incidence
Neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Limb salvage using preoperative intraarterial adriamycin and radiation therapy for extremity soft tissue sarcomas. / Morton, D. L.; Eilber, F. R.; Weisenburger, T. H.; Townsend, Courtney; Mirra, J. M.

In: Australian and New Zealand Journal of Surgery, Vol. 48, No. 1, 1978, p. 56-59.

Research output: Contribution to journalArticle

@article{83627dca23dc4c2a9ec91da98ef4ede8,
title = "Limb salvage using preoperative intraarterial adriamycin and radiation therapy for extremity soft tissue sarcomas",
abstract = "Surgical therapy has been the accepted method for management of most soft tissue sarcomas of the extremities, although it has been associated frequently with local treatment failure. Even when local control was achieved, over 50{\%} of the patients with soft tissue sarcomas eventually developed and succumbed to distant metastases of their disease. Therefore, single modality therapy for soft tissue sarcomas by operation alone results in an unacceptably high incidence of treatment failure. Fortunately, new adjuvant treatment techniques have been developed that seem to have activity against these neoplasms. It is the purpose of this article to discuss our experience with a number of these techniques.",
author = "Morton, {D. L.} and Eilber, {F. R.} and Weisenburger, {T. H.} and Courtney Townsend and Mirra, {J. M.}",
year = "1978",
language = "English (US)",
volume = "48",
pages = "56--59",
journal = "ANZ Journal of Surgery",
issn = "1445-1433",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Limb salvage using preoperative intraarterial adriamycin and radiation therapy for extremity soft tissue sarcomas

AU - Morton, D. L.

AU - Eilber, F. R.

AU - Weisenburger, T. H.

AU - Townsend, Courtney

AU - Mirra, J. M.

PY - 1978

Y1 - 1978

N2 - Surgical therapy has been the accepted method for management of most soft tissue sarcomas of the extremities, although it has been associated frequently with local treatment failure. Even when local control was achieved, over 50% of the patients with soft tissue sarcomas eventually developed and succumbed to distant metastases of their disease. Therefore, single modality therapy for soft tissue sarcomas by operation alone results in an unacceptably high incidence of treatment failure. Fortunately, new adjuvant treatment techniques have been developed that seem to have activity against these neoplasms. It is the purpose of this article to discuss our experience with a number of these techniques.

AB - Surgical therapy has been the accepted method for management of most soft tissue sarcomas of the extremities, although it has been associated frequently with local treatment failure. Even when local control was achieved, over 50% of the patients with soft tissue sarcomas eventually developed and succumbed to distant metastases of their disease. Therefore, single modality therapy for soft tissue sarcomas by operation alone results in an unacceptably high incidence of treatment failure. Fortunately, new adjuvant treatment techniques have been developed that seem to have activity against these neoplasms. It is the purpose of this article to discuss our experience with a number of these techniques.

UR - http://www.scopus.com/inward/record.url?scp=0018147314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018147314&partnerID=8YFLogxK

M3 - Article

C2 - 96785

AN - SCOPUS:0018147314

VL - 48

SP - 56

EP - 59

JO - ANZ Journal of Surgery

JF - ANZ Journal of Surgery

SN - 1445-1433

IS - 1

ER -