Limited clinical diagnostic specificity of technetium-99m stannous pyrophosphate myocardial imaging in acute myocardial infarction

Masood Ahmad, Jerzy P. Dubiel, K. William Logan, Thomas A. Verdon, Richard H. Martin

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

To test the sensitivity and specificity of technetium-99m stannous pyrophosphate myocardial imaging in the diagnosis of acute myocardial infarction, myocardial scintigrams were performed in 115 patients. Positive scintigrams were found in all 48 patients with acute myocardial infarction; uptake was localized in 29 patients with transmural infarction and diffuse in 2 patients with transmural infarction and in the remaining 17 patients with subendocardial myocardial infarction. Positive scintigrams were also found in 31 of 67 patients without clinical evidence of acute myocardial infarction. Diffusely positive scintigrams were found in 3 of 3 patients with unstable angina pectoris, 7 of 30 patients with stable angina pectoris, 4 of 13 patients who had undergone aortocoronary bypass surgery, 4 of 4 patients with congestive cardiomyopathy and 1 patient studied 1 day after direct current cardioversion. Localized uptake of 99mTc-pyrophosphate was found in 9 of 10 patients with left ventricular aneurysm and in 3 of 13 patients after aortocoronary bypass surgery. All four patients with atypical chest pain and two patients with pericarditis had normal scintigrams. Our data confirm the previously reported sensitivity of 99mTc-pyrophosphate imaging in detection of acute myocardial infarction but indicate that positive scintigrams are not specific for this entity.

Original languageEnglish (US)
Pages (from-to)50-54
Number of pages5
JournalThe American Journal of Cardiology
Volume39
Issue number1
DOIs
StatePublished - 1977
Externally publishedYes

Fingerprint

Technetium
Myocardial Infarction
Technetium Tc 99m Pyrophosphate
technetium Tc 99m stannous pyrophosphate
Coronary Artery Bypass
Infarction
Electric Countershock
Pericarditis
Stable Angina
Unstable Angina
Dilated Cardiomyopathy
Chest Pain
Aneurysm

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Limited clinical diagnostic specificity of technetium-99m stannous pyrophosphate myocardial imaging in acute myocardial infarction. / Ahmad, Masood; Dubiel, Jerzy P.; Logan, K. William; Verdon, Thomas A.; Martin, Richard H.

In: The American Journal of Cardiology, Vol. 39, No. 1, 1977, p. 50-54.

Research output: Contribution to journalArticle

Ahmad, Masood ; Dubiel, Jerzy P. ; Logan, K. William ; Verdon, Thomas A. ; Martin, Richard H. / Limited clinical diagnostic specificity of technetium-99m stannous pyrophosphate myocardial imaging in acute myocardial infarction. In: The American Journal of Cardiology. 1977 ; Vol. 39, No. 1. pp. 50-54.
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