Loa loa infection as a cause of migratory angioedema

Report of three cases from the Texas Medical Center

Robert M. Rakita, A. Clinton White, Marcia A. Kielhofner

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Loa loa is a filarial parasite that is endemic in West and Central Africa. Expatriates infected with L. loa commonly develop characteristic migratory angioedema called Calabar swellings. We describe three patients who presented with classical Calabar swellings for whom the diagnosis of loiasis was delayed. Unusual features that were present included a leukocytoclastic vasculitis seen on skin biopsy (case 1), a relatively short exposure to an area of endemicity (cases 1 and 3), and a normal eosinophil count on initial evaluation (cases 2 and 3). We discuss the characteristic clinical manifestations of, pathological findings of, and therapy for loiasis. With the increased frequency of international travel, L. loa infection must be considered in the differential diagnosis for patients with migratory angioedema, urticarial vasculitis, or eosinophilia.

Original languageEnglish
Pages (from-to)691-694
Number of pages4
JournalClinical Infectious Diseases
Volume17
Issue number4
StatePublished - Oct 1993
Externally publishedYes

Fingerprint

Loa
Angioedema
Loiasis
Infection
Central Africa
Western Africa
Eosinophilia
Vasculitis
Eosinophils
Parasites
Differential Diagnosis
Biopsy
Skin
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

Loa loa infection as a cause of migratory angioedema : Report of three cases from the Texas Medical Center. / Rakita, Robert M.; White, A. Clinton; Kielhofner, Marcia A.

In: Clinical Infectious Diseases, Vol. 17, No. 4, 10.1993, p. 691-694.

Research output: Contribution to journalArticle

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