Abstract
Early mammographic detection of nonpalpable breast lesions has led to the increasing use of stereotactic core biopsies for tissue diagnosis. Tumor seeding the needle tract is a theorectical concern; the incidence and clinical significance of this potential complication are unknown. We report three cases of subcutaneous breast cancer recurrence at the stereotactic biopsy site after definitive treatment of the primary breast tumor. Two cases were clinically evident and relevant; the third was detected in the preclinical, microscopic state. All three patients underwent multiple passes during stereotactic large-core biopsies (14 gauge needle) followed by modified radical mastectomy. Two patients developed a subcutaneous recurrence at the site of the previous biopsy 12 and 17 months later; one had excision of the skin and dermis at the time of mastectomy revealing tumor cells locally. In summary, clinically relevant recurrence from tumor cells seeding the needle tract is reported in two patients after definitive surgical therapy (without adjuvant radiation therapy). Often, the biopsy site is outside the boundaries of surgical resection. Since the core needle biopsy exit site represents a potential area of malignant seeding and subsequent tumor recurrence, we recommend excising the stereotactic core biopsy tract at the time of definitive surgical resection of the primary tumor.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 124-127 |
| Number of pages | 4 |
| Journal | Breast Journal |
| Volume | 7 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
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Keywords
- Breast cancer recurrence
- Needle tract seeding
- Stereotactic biopsy
ASJC Scopus subject areas
- Internal Medicine
- Oncology
Cite this
Local recurrence of breast cancer in the stereotactic core needle biopsy site : Case reports and review of the literature. / Chao, Celia; Torosian, Michael H.; Boraas, Marcia C.; Sigurdson, Elin R.; Hoffman, John P.; Eisenberg, Burton L.; Fowble, Barbara.
In: Breast Journal, Vol. 7, No. 2, 2001, p. 124-127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Local recurrence of breast cancer in the stereotactic core needle biopsy site
T2 - Case reports and review of the literature
AU - Chao, Celia
AU - Torosian, Michael H.
AU - Boraas, Marcia C.
AU - Sigurdson, Elin R.
AU - Hoffman, John P.
AU - Eisenberg, Burton L.
AU - Fowble, Barbara
PY - 2001
Y1 - 2001
N2 - Early mammographic detection of nonpalpable breast lesions has led to the increasing use of stereotactic core biopsies for tissue diagnosis. Tumor seeding the needle tract is a theorectical concern; the incidence and clinical significance of this potential complication are unknown. We report three cases of subcutaneous breast cancer recurrence at the stereotactic biopsy site after definitive treatment of the primary breast tumor. Two cases were clinically evident and relevant; the third was detected in the preclinical, microscopic state. All three patients underwent multiple passes during stereotactic large-core biopsies (14 gauge needle) followed by modified radical mastectomy. Two patients developed a subcutaneous recurrence at the site of the previous biopsy 12 and 17 months later; one had excision of the skin and dermis at the time of mastectomy revealing tumor cells locally. In summary, clinically relevant recurrence from tumor cells seeding the needle tract is reported in two patients after definitive surgical therapy (without adjuvant radiation therapy). Often, the biopsy site is outside the boundaries of surgical resection. Since the core needle biopsy exit site represents a potential area of malignant seeding and subsequent tumor recurrence, we recommend excising the stereotactic core biopsy tract at the time of definitive surgical resection of the primary tumor.
AB - Early mammographic detection of nonpalpable breast lesions has led to the increasing use of stereotactic core biopsies for tissue diagnosis. Tumor seeding the needle tract is a theorectical concern; the incidence and clinical significance of this potential complication are unknown. We report three cases of subcutaneous breast cancer recurrence at the stereotactic biopsy site after definitive treatment of the primary breast tumor. Two cases were clinically evident and relevant; the third was detected in the preclinical, microscopic state. All three patients underwent multiple passes during stereotactic large-core biopsies (14 gauge needle) followed by modified radical mastectomy. Two patients developed a subcutaneous recurrence at the site of the previous biopsy 12 and 17 months later; one had excision of the skin and dermis at the time of mastectomy revealing tumor cells locally. In summary, clinically relevant recurrence from tumor cells seeding the needle tract is reported in two patients after definitive surgical therapy (without adjuvant radiation therapy). Often, the biopsy site is outside the boundaries of surgical resection. Since the core needle biopsy exit site represents a potential area of malignant seeding and subsequent tumor recurrence, we recommend excising the stereotactic core biopsy tract at the time of definitive surgical resection of the primary tumor.
KW - Breast cancer recurrence
KW - Needle tract seeding
KW - Stereotactic biopsy
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UR - http://www.scopus.com/inward/citedby.url?scp=0035039836&partnerID=8YFLogxK
U2 - 10.1046/j.1524-4741.2001.007002124.x
DO - 10.1046/j.1524-4741.2001.007002124.x
M3 - Article
C2 - 11328321
AN - SCOPUS:0035039836
VL - 7
SP - 124
EP - 127
JO - Breast Journal
JF - Breast Journal
SN - 1075-122X
IS - 2
ER -