Abstract
The present study demonstrates a significant number of calcitonin gene-related peptide (CGRP) immunolabeled unmyelinated axons in the C3 fasciculus gracilis of the rat. Approximately 88% of these axons are lost following dorsal rhizotomies from midthoracic levels caudally. Assuming that CGRP labels primary afferent axons, these findings support the hypothesis that there are significant numbers of long ascending unmyelinated primary afferent axons in the dorsal columns of the rat. If these findings can be generalized, they may have clinical import.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6-10 |
| Number of pages | 5 |
| Journal | Neuroscience Letters |
| Volume | 108 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 1 1990 |
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Keywords
- Calcitonin gene-related peptide
- Dorsal column
- Primary afferent
- Unmyelinated axon
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Long ascending unmyelinated primary afferent axons in the rat dorsal column : Immunohistochemical localizations. / Patterson, Joel; Coggeshall, R. E.; Lee, W. T.; Chung, K.
In: Neuroscience Letters, Vol. 108, No. 1-2, 01.01.1990, p. 6-10.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long ascending unmyelinated primary afferent axons in the rat dorsal column
T2 - Immunohistochemical localizations
AU - Patterson, Joel
AU - Coggeshall, R. E.
AU - Lee, W. T.
AU - Chung, K.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - The present study demonstrates a significant number of calcitonin gene-related peptide (CGRP) immunolabeled unmyelinated axons in the C3 fasciculus gracilis of the rat. Approximately 88% of these axons are lost following dorsal rhizotomies from midthoracic levels caudally. Assuming that CGRP labels primary afferent axons, these findings support the hypothesis that there are significant numbers of long ascending unmyelinated primary afferent axons in the dorsal columns of the rat. If these findings can be generalized, they may have clinical import.
AB - The present study demonstrates a significant number of calcitonin gene-related peptide (CGRP) immunolabeled unmyelinated axons in the C3 fasciculus gracilis of the rat. Approximately 88% of these axons are lost following dorsal rhizotomies from midthoracic levels caudally. Assuming that CGRP labels primary afferent axons, these findings support the hypothesis that there are significant numbers of long ascending unmyelinated primary afferent axons in the dorsal columns of the rat. If these findings can be generalized, they may have clinical import.
KW - Calcitonin gene-related peptide
KW - Dorsal column
KW - Primary afferent
KW - Unmyelinated axon
UR - http://www.scopus.com/inward/record.url?scp=0025058499&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025058499&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(90)90697-8
DO - 10.1016/0304-3940(90)90697-8
M3 - Article
C2 - 2304639
AN - SCOPUS:0025058499
VL - 108
SP - 6
EP - 10
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 1-2
ER -