Long ascending unmyelinated primary afferent axons in the rat dorsal column: Immunohistochemical localizations

Joel Patterson, R. E. Coggeshall, W. T. Lee, K. Chung

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The present study demonstrates a significant number of calcitonin gene-related peptide (CGRP) immunolabeled unmyelinated axons in the C3 fasciculus gracilis of the rat. Approximately 88% of these axons are lost following dorsal rhizotomies from midthoracic levels caudally. Assuming that CGRP labels primary afferent axons, these findings support the hypothesis that there are significant numbers of long ascending unmyelinated primary afferent axons in the dorsal columns of the rat. If these findings can be generalized, they may have clinical import.

Original languageEnglish (US)
Pages (from-to)6-10
Number of pages5
JournalNeuroscience Letters
Volume108
Issue number1-2
DOIs
StatePublished - Jan 1 1990

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Axons
Calcitonin Gene-Related Peptide
Rhizotomy

Keywords

  • Calcitonin gene-related peptide
  • Dorsal column
  • Primary afferent
  • Unmyelinated axon

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Long ascending unmyelinated primary afferent axons in the rat dorsal column : Immunohistochemical localizations. / Patterson, Joel; Coggeshall, R. E.; Lee, W. T.; Chung, K.

In: Neuroscience Letters, Vol. 108, No. 1-2, 01.01.1990, p. 6-10.

Research output: Contribution to journalArticle

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