Long polar fimbriae contribute to colonization by Escherichia coli O157: H7 in vivo

Dianna M. Jordan, Nancy Cornick, Alfredo Torres, Evelyn A. Dean-Nystrom, James B. Kaper, Harley W. Moon

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Abstract

The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.

Original languageEnglish (US)
Pages (from-to)6168-6171
Number of pages4
JournalInfection and Immunity
Volume72
Issue number10
DOIs
StatePublished - Oct 2004

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ASJC Scopus subject areas

  • Immunology

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