Long polar fimbriae contribute to colonization by Escherichia coli O157:H7 in vivo

Dianna M. Jordan, Nancy Cornick, Alfredo G. Torres, Evelyn A. Dean-Nystrom, James B. Kaper, Harley W. Moon

Research output: Contribution to journalArticlepeer-review

79 Scopus citations

Abstract

The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.

Original languageEnglish (US)
Pages (from-to)6168-6171
Number of pages4
JournalInfection and immunity
Volume72
Issue number10
DOIs
StatePublished - Oct 2004

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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