Long-term disease surveillance in Bandundu region, Democratic Republic of the Congo: A model for early detection and prevention of Ebola hemorrhagic fever

Ethleen S. Lloyd, Sherif R. Zaki, Pierre E. Rollin, Kweteminga Tshioko, Mpia A. Bwaka, Thomas G. Ksiazek, Philippe Calain, Wun Ju Shieh, M. Kader Kondé, Eric Verchueren, Helen N. Perry, Lubaki Manguindula, Jean Kabwau, Roger Ndambi, C. J. Peters

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

After the large-scale outbreak of Ebola hemorrhagic fever (EHF) in Bandundu region, Democratic Republic of the Congo, a program was developed to help detect and prevent future outbreaks of EHF in the region. The long-term surveillance and prevention strategy is based on early recognition by physicians, immediate initiation of enhanced barrier-nursing practices, and the use of an immunohistochemical diagnostic test performed on formalin- fixed skin specimens of patients who die of suspected viral hemorrhagic fever. The program was implemented in September 1995 during a 4-day workshop with 28 local physicians representing 17 of 22 health zones in the region. Specimen collection kits were distributed to clinics in participating health zones, and a follow-up evaluation was conducted after 6 months. The use of a formalin-fixed skin specimen for laboratory confirmation of EHF can provide an appropriate method for EHF surveillance when linked with physician training, use of viral hemorrhagic fever isolation precautions, and follow- up investigation.

Original languageEnglish (US)
Pages (from-to)S274-S280
JournalJournal of Infectious Diseases
Volume179
Issue numberSUPPL. 1
StatePublished - Mar 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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    Lloyd, E. S., Zaki, S. R., Rollin, P. E., Tshioko, K., Bwaka, M. A., Ksiazek, T. G., Calain, P., Shieh, W. J., Kondé, M. K., Verchueren, E., Perry, H. N., Manguindula, L., Kabwau, J., Ndambi, R., & Peters, C. J. (1999). Long-term disease surveillance in Bandundu region, Democratic Republic of the Congo: A model for early detection and prevention of Ebola hemorrhagic fever. Journal of Infectious Diseases, 179(SUPPL. 1), S274-S280.