TY - JOUR
T1 - Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device
T2 - a Retrospective Multicenter Observational Study
AU - on behalf of the WorldWideWEB Consortium
AU - El Naamani, Kareem
AU - Mastorakos, Panagiotis
AU - Adeeb, Nimer
AU - Lan, Mathews
AU - Castiglione, James
AU - Khanna, Omaditya
AU - Diestro, Jose Danilo Bengzon
AU - McLellan, Rachel M.
AU - Dibas, Mahmoud
AU - Vranic, Justin E.
AU - Aslan, Assala
AU - Cuellar-Saenz, Hugo H.
AU - Guenego, Adrien
AU - Carnevale, Joseph
AU - Saliou, Guillaume
AU - Ulfert, Christian
AU - Möhlenbruch, Markus
AU - Foreman, Paul M.
AU - Vachhani, Jay A.
AU - Hafeez, Muhammad U.
AU - Waqas, Muhammad
AU - Tutino, Vincent M.
AU - Rabinov, James D.
AU - Ren, Yifan
AU - Michelozzi, Caterina
AU - Spears, Julian
AU - Panni, Pietro
AU - Griessenauer, Christoph J.
AU - Asadi, Hamed
AU - Regenhardt, Robert W.
AU - Stapleton, Christopher J.
AU - Ghozy, Sherief
AU - Siddiqui, Adnan
AU - Patel, Nirav J.
AU - Kan, Peter
AU - Boddu, Srikanth
AU - Knopman, Jared
AU - Aziz-Sultan, Mohammad A.
AU - Zanaty, Mario
AU - Ghosh, Ritam
AU - Abbas, Rawad
AU - Amllay, Abdelaziz
AU - Tjoumakaris, Stavropoula I.
AU - Gooch, Michael R.
AU - Cancelliere, Nicole M.
AU - Herial, Nabeel A.
AU - Rosenwasser, Robert H.
AU - Zarzour, Hekmat
AU - Schmidt, Richard F.
AU - Pereira, Vitor Mendes
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023
Y1 - 2023
N2 - The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.
AB - The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value.
KW - Aneurysm
KW - Imaging
KW - Obliteration
KW - Positive predictive value
KW - WEB device
UR - http://www.scopus.com/inward/record.url?scp=85159143773&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85159143773&partnerID=8YFLogxK
U2 - 10.1007/s12975-023-01153-5
DO - 10.1007/s12975-023-01153-5
M3 - Article
C2 - 37165289
AN - SCOPUS:85159143773
SN - 1868-4483
JO - Translational Stroke Research
JF - Translational Stroke Research
ER -