Long‐term colchicine administration leading to colchicine toxicity and death

Extracts from the Colchicum autumnale plant have been used to treat gout since the sixth century, and many instances of accidental or intentional overdose have been reported. Although a clinical syndrome due to acute colchicine intoxication is wellknown, we know of no reports of its occurrence while a patient was taking usual prophylactic doses. The following case study may be the first reported example of such an event.