Lytic/'DPT' cocktail: Time for rational and safe alternatives

W. R. Snodgrass, W. F. Dodge

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Owing to the frequent occurrence of orthostatic hypotension, ventilatory (respiratory) depression, the DPT/lytic cocktail combination of drugs is no longer recommended. This article reviews the goals of anesthetic premedication in children, physiologic considerations in pediatric premedication, toxicities of certain premedication drug regimens, and alternatives to the use of DPT/lytic cocktail.

Original languageEnglish (US)
Pages (from-to)1285-1291+x
JournalPediatric Clinics of North America
Issue number5
StatePublished - 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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