Magnetic resonance imaging in early detection of rheumatoid arthritis

Jamshid Tehranzadeh, Oganes Ashikyan, Jane Dascalos

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) is the modality of choice in early diagnosis and management of rheumatoid arthritis (RA). The pathologic processes in RA involve synovitis, joint effusion, proliferation of fibrovascular connective tissue, and the formation of pannus. Other imaging techniques available for imaging of RA include ultrasound, scintigraphy, computed tomography, and plain radiography (PR). MRI provides high sensitivity in detecting inflammatory changes in the joints. Several studies report high intra- and interobserver reliability and low variation for MRI. MRI allows detection and, in some cases, quantification of synovial changes. Dynamic MRI is a new technique that utilizes rate of synovial enhancement in evaluation of inflammatory changes. MRI allows visualization of erosions in three orthogonal planes. MRI has been shown in many studies to have much greater sensitivity than PR in detecting erosions. Use of a contrast agent further increases the sensitivity in detecting erosions and differentiates and outlines synovial proliferation from fluid collection. Other manifestations of RA such as intraosseous cysts, tenosynovitis, bone marrow edema, and carpal tunnel syndrome can also be visualized on magnetic resonance images. Advances in MRI include contrast-enhancement, dynamic, and quantitative techniques. MRI assists in the early detection of RA, which allows earlier initiation of treatment with disease-modifying therapies.

Original languageEnglish (US)
Pages (from-to)79-94
Number of pages16
JournalSeminars in Musculoskeletal Radiology
Volume7
Issue number2
StatePublished - Jun 2003

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Rheumatoid Arthritis
Magnetic Resonance Imaging
Radiography
Joints
Tenosynovitis
Carpal Tunnel Syndrome
Synovitis
Synovial Fluid
Pathologic Processes
Radionuclide Imaging
Connective Tissue
Contrast Media
Cysts
Early Diagnosis
Edema
Magnetic Resonance Spectroscopy
Bone Marrow
Tomography

Keywords

  • Imaging techniques
  • Magnetic resonance imaging
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Surgery

Cite this

Tehranzadeh, J., Ashikyan, O., & Dascalos, J. (2003). Magnetic resonance imaging in early detection of rheumatoid arthritis. Seminars in Musculoskeletal Radiology, 7(2), 79-94.

Magnetic resonance imaging in early detection of rheumatoid arthritis. / Tehranzadeh, Jamshid; Ashikyan, Oganes; Dascalos, Jane.

In: Seminars in Musculoskeletal Radiology, Vol. 7, No. 2, 06.2003, p. 79-94.

Research output: Contribution to journalArticle

Tehranzadeh, J, Ashikyan, O & Dascalos, J 2003, 'Magnetic resonance imaging in early detection of rheumatoid arthritis', Seminars in Musculoskeletal Radiology, vol. 7, no. 2, pp. 79-94.
Tehranzadeh, Jamshid ; Ashikyan, Oganes ; Dascalos, Jane. / Magnetic resonance imaging in early detection of rheumatoid arthritis. In: Seminars in Musculoskeletal Radiology. 2003 ; Vol. 7, No. 2. pp. 79-94.
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