Magnetic Tweezers in Cell Biology

Monica Tanase, Nicolas Biais, Michael Sheetz

Research output: Chapter in Book/Report/Conference proceedingChapter

78 Scopus citations

Abstract

We discuss herein the theory as well as some design considerations of magnetic tweezers. This method of generating force on magnetic particles bound to biological entities is shown to have a number of advantages over other techniques: forces are exerted in noncontact mode, they can be large in magnitude (order of 10 nanonewtons), and adjustable in direction, static or oscillatory. One apparatus built in our laboratory is described in detail, along with examples of experimental applications and results.

Original languageEnglish (US)
Title of host publicationCell Mechanics
EditorsYuLi Wang, Dennis Discher
Pages473-493
Number of pages21
DOIs
StatePublished - Jul 3 2007
Externally publishedYes

Publication series

NameMethods in Cell Biology
Volume83
ISSN (Print)0091-679X

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ASJC Scopus subject areas

  • Cell Biology

Cite this

Tanase, M., Biais, N., & Sheetz, M. (2007). Magnetic Tweezers in Cell Biology. In Y. Wang, & D. Discher (Eds.), Cell Mechanics (pp. 473-493). (Methods in Cell Biology; Vol. 83). https://doi.org/10.1016/S0091-679X(07)83020-2