Maintenance of Toscana virus in phlebotomus perniciosus by vertical transmission

R. B. Tesh, G. B. Modi

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Toscana virus was maintained in a laboratory colony of Phlebotomus perniciosus by vertical (transovarial) transmission for 13 consecutive generations over a 23-month period. No significant biological changes were noted in the virus after prolonged vertical passage in the sand flies, and transovarially infected females were able to transmit the agent by bite to susceptible animals. Chronic infection of Ph. perniciosus with Toscana virus had no apparent effect on the insects' rate of eclosion. In the absence of selection and with random matings, the virus infection rates in each subsequent generation of the colony decreased, suggesting that Toscana virus cannot be maintained in Ph. perniciosus by transovarial transmission alone. Alternative mechanisms for virus maintenance are discussed.

Original languageEnglish (US)
Pages (from-to)189-193
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume36
Issue number1
StatePublished - 1987
Externally publishedYes

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Sandfly fever Naples virus
Phlebotomus
Maintenance
Viruses
Psychodidae
Virus Diseases
Bites and Stings
Insects
Infection

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Maintenance of Toscana virus in phlebotomus perniciosus by vertical transmission. / Tesh, R. B.; Modi, G. B.

In: American Journal of Tropical Medicine and Hygiene, Vol. 36, No. 1, 1987, p. 189-193.

Research output: Contribution to journalArticle

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