Management of a sabiá virus-infected patient in a US hospital

Lori R. Armstrong, Louise Marie Dembry, Petrie M. Rainey, Mark B. Russi, Ali S. Khan, Steven H. Fischer, Stephen C. Edberg, Thomas Ksiazek, Pierre E. Rollin, C. J. Peters

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

OBJECTIVE: To describe the hospital precautions used to isolate a Sabiá virus (arenavirus: Arenaviridae)-infected patient in a US hospital and to protect hospital staff and visitors. DESIGN: Investigation of a single case of arenavirus laboratory-acquired infection and associated case-contacts. SETTING: A 900-bed, tertiary-care, university-affiliated medical center. PATIENTS OR OTHER PARTICIPANTS: The casepatient became ill with Sabiá virus infection. The case-contacts consisted of healthcare workers, coworkers, friends, and relatives of the case-patient. INTERVENTION: Enhanced isolation precautions for treatment of a viral hemorrhagic fever (VHF) patient were implemented in the clinical laboratory and patient-care setting to prevent nosocomial transmission. The enhanced precautions included preventing aerosol spread of the virus from the patient or his clinical specimens. All case-contacts were tested for Sabiá virus antibodies and monitored for signs and symptoms of early disease. RESULTS: No cases of secondary infection occurred among 142 case-contacts. CONCLUSIONS: With the frequency of worldwide travel, patients with VHF can be admitted to a local hospital at any time in the United States. The use of enhanced isolation precautions for VHF appeared to be effective in preventing secondary cases by limiting the number of contacts and promoting proper handling of laboratory specimens. Patients with VHF can be managed safely in a local hospital settine. provided that appropriate precautions are planned and implemented.

Original languageEnglish (US)
Pages (from-to)176-182
Number of pages7
JournalInfection Control and Hospital Epidemiology
Volume20
Issue number3
DOIs
StatePublished - 1999
Externally publishedYes

Fingerprint

Viral Hemorrhagic Fevers
Viruses
Arenavirus
Arenaviridae
Laboratory Infection
Specimen Handling
Virus Diseases
Tertiary Healthcare
Aerosols
Coinfection
Signs and Symptoms
Patient Care
Delivery of Health Care
Antibodies

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Armstrong, L. R., Dembry, L. M., Rainey, P. M., Russi, M. B., Khan, A. S., Fischer, S. H., ... Peters, C. J. (1999). Management of a sabiá virus-infected patient in a US hospital. Infection Control and Hospital Epidemiology, 20(3), 176-182. https://doi.org/10.1086/501607

Management of a sabiá virus-infected patient in a US hospital. / Armstrong, Lori R.; Dembry, Louise Marie; Rainey, Petrie M.; Russi, Mark B.; Khan, Ali S.; Fischer, Steven H.; Edberg, Stephen C.; Ksiazek, Thomas; Rollin, Pierre E.; Peters, C. J.

In: Infection Control and Hospital Epidemiology, Vol. 20, No. 3, 1999, p. 176-182.

Research output: Contribution to journalArticle

Armstrong, LR, Dembry, LM, Rainey, PM, Russi, MB, Khan, AS, Fischer, SH, Edberg, SC, Ksiazek, T, Rollin, PE & Peters, CJ 1999, 'Management of a sabiá virus-infected patient in a US hospital', Infection Control and Hospital Epidemiology, vol. 20, no. 3, pp. 176-182. https://doi.org/10.1086/501607
Armstrong LR, Dembry LM, Rainey PM, Russi MB, Khan AS, Fischer SH et al. Management of a sabiá virus-infected patient in a US hospital. Infection Control and Hospital Epidemiology. 1999;20(3):176-182. https://doi.org/10.1086/501607
Armstrong, Lori R. ; Dembry, Louise Marie ; Rainey, Petrie M. ; Russi, Mark B. ; Khan, Ali S. ; Fischer, Steven H. ; Edberg, Stephen C. ; Ksiazek, Thomas ; Rollin, Pierre E. ; Peters, C. J. / Management of a sabiá virus-infected patient in a US hospital. In: Infection Control and Hospital Epidemiology. 1999 ; Vol. 20, No. 3. pp. 176-182.
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